Examples of using Integrin in English and their translations into Chinese
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They believe Tinagl1 works partly by inhibiting integrins.
CD47 interacts with several membrane integrins, most commonly integrin avb3.
Integrin beta-2(CD18) is a protein that in humans is encoded by the ITGB2 gene.
A conserved RGD motif is found in this protein,and this is potentially involved in integrin recognition.
These findings suggest that integrin α7 represents an important new target for cancer therapy and prevention.
We offer a broad range of gene-specific products for studying integrin cell signaling and signal transduction.
Selective integrin endocytosis is driven by interactions between the integrin α-chain and AP2.
The researchers learned that fever-induced Hsp90 binds to the integrin tail and induces integrin activation.
Integrins also help cells attach to one another and are involved in transmitting chemical signals between cells and the ECM.
This cellular communication process features early integrin engagement and T cell motility arrest, referred to as the"stop signal.".
Similarly, the researchers found no visiblemetastasis in mice with tumors in which levels of normal integrin á7 had been increased.
By inhibiting alpha4beta7 integrin, vedolizumab may limit the ability of certain white blood cells to infiltrate gut tissues.
It will provide an experimental basis for the design of novel drugs for the treatment of cervical cancer,based on integrin inhibitors.".
But when we combined integrin inhibition and chemotherapy, we killed over 90 percent of the single cells in our cultures.”.
They found that a molecular pathway that facilitates the recycling of integrin within the cell, called Arf6-AMP1-PRKD2, also facilitates the localization of mitochondria.
Integrins beta1, alpha6, and alpha3 contribute to mechanical strain-induced differentiation of fetal lung type II epithelial cells via distinct mechanisms.
Modulation of these molecules, particularly αv integrin family, has exhibited profound effects on fibrosis in multiple organ and disease state.
Integrin beta-3(β3) or CD61 is a protein that in humans is encoded by the ITGB3 gene.[5] CD61 is a cluster of differentiation found on thrombocytes.[6].
Finally, to investigate whether normal integrin á7 possesses tumor suppressor activity, the researchers implanted human cancer cells into immune deficient mice.
SYKis activated by C-type lectins and integrins, and activates new targets, including the CARD9- BCL-10- MALT1 pathway and the NLRP3 inflammasome[1].
They found mutations in the integrin α7 gene, particularly those that resulted in an abnormally shortened protein product, or truncation, in 16 of 28 prostate cancers.