What is the translation of " OFF-TARGET " in Chinese?

• 脱靶
• 非靶

Examples of using Off-target in English and their translations into Chinese

A: First, regarding off-target by sequencing.
贺：首先，关于对脱靶进行测序。

Off-target has been a major problem for CRISPR/ Cas9 technology.
脱靶一直是CRISPR/Cas9技术的主要困扰。

A: First, regarding off-target by sequencing.
答：首先，关于通过测序的脱靶。

To date, all approved IL-2 therapies unfortunately cause preferential activation of these off-target cells.
迄今为止，所有批准的IL-2疗法往往不幸地导致这些非靶细胞的优先激活。

Different guides can have different off-target effects depending on how they are used.
不同的向导可以有不同的偏离目标的效果，取决于它们的使用方式。

To date, all approved IL-2 therapies unfortunately cause preferential activation of these off-target cells.
迄今为止，所有批准的IL-2疗法都会引起这些由于脱靶而产生的严重副作用。

This off-target is an intergenic region, although we can't confirm whether this is inheritance or due to editing.
这个脱靶位点处在非基因区域，虽然我们不能确定这是遗传还是编辑造成的。

Rather, the drugs induced cell death through off-target mechanisms;
相反，药物通过脱靶机制诱导细胞死亡;

He contends that the babies have no such off-target mutations, although some scientists are skeptical of the evidence offered so far.
他认为这些婴儿没有这种脱靶突变，尽管一些科学家对目前提供的证据持怀疑态度。

Different enzymes(“molecular scissors”) or more precise delivery vehicles can reduce off-target activity.
不同的酶（“分子剪刀”）或更精确的运载工具可以减少Off-targetactivity。

Currently, no single method could detect all these types of off-target mutations, especially when they occur at a very low baby.
目前尚没有哪一种方法可以检测所有这类脱靶突变，特别是当它们的发生频率非常低时。

But the Cas9-sgRNA complex can also bind to DNA that doesn't exactly match, leading to undesirable off-target cutting.
但是这种Cas9-sgRNA复合物也能够结合到不那么精确匹配的DNA上，从而导致不想要的脱靶切割。

That's risky because CRISPR can cause unintentional or off-target edits, meaning it may cut DNA it isn't supposed to.
那是有风险的，因为CRISPR会导致无意的或非目标的编辑，这意味着可能会切掉不应该被削减的DNA。

These particles travel a shorter distance than the beta particles emitted by traditional isotopes, which means their off-target effect is limited.
这些粒子的行进距离比传统同位素发射的β粒子短，这意味着它们的脱靶作用是有限的。

Scientists design guide RNAs to minimize off-target, unintended cutting, but there is always a risk that extra cutting could occur.
科学家们设计gRNA旨在最大限度地减少脱靶切割和不想要的切割，但总是存在可能发生额外切割的风险。

Intensive monitoring of the patients, including blood draws to study their altered T cells, confirmed that CRISPR had left some off-target changes.
对患者的密集监测，包括抽血以研究他们改变的T细胞，证实了CRISPR留下了一些脱靶改变。

Aside from its progestogenic activity, desogestrel also has some off-target hormonal activity at other steroid hormone receptors(see below).
除了其孕激素活性外，去氧孕烯还对其他类固醇激素受体具有一些脱靶激素活性（见下文）。

The latest results also indicate that the single-base editing tools engineered with CRISPR/ Cas9 are very specific and no off-target editing was detected.
最新的结果也表明，利用CRISPR/Cas9改造的单碱基编辑工具特异性非常高，没有检测到脱靶编辑。

Last fall, you stated that the world was off-target for meeting the Millennium Development Goal of halving hunger by the year 2015.
去年秋季，你指出在实现到2015年将饥饿人数减半这一千年发展目标方面世界未能达到指标。

This is not the team's fault, as there will always be limitations in detecting off-target and mosaicism and we can only get a partial picture.
这不是团队的错，因为在检测偏离目标和马赛克的过程中总是存在局限性，我们只能得到部分了解。

In order to minimize unexpected off-target effects, the SGC also strives to find a chemotype-matched negative control for each chemical probe.
为了尽可能降低脱靶的意外效应，SGC还致力于为每种化学探针寻找一种化学构型匹配的阴性对照。

Cellectis' Choulika agrees new vector technologies are needed and adds that off-target editing is another problem that must be solved.
Cellectis的Choulika博士同意新的载体技术是必需的，并补充说，脱靶编辑是另一个必须解决的问题。

Finally, we analyzed potential off-targets of five sgRNAs in gene-modified mice and ESC lines and identified off-target mutations in only rare instances.
最后，该研究分析了基因修饰小鼠和ESC系中5种sgRNA的潜在脱靶，并在极少数情况下鉴定了脱靶突变；.

The tagged virus particle method, for example, may miss some off-target cleavage, because the viral tags may not bind to every single break.
比如，采用带有标记的病毒颗粒的方法可能会遗失一些脱靶切割，因为病毒标记可能并不结合到每个单裂口。

If we can convincingly show that there is no off-target activity in the genome, this system can be used in different types of genome editing.
如果我们能令人信服地证明基因组中没有意外脱靶，这个系统就可以被用于不同类型的基因编辑。

Embryo targeting at single or few cell stage of life, any off-target would pose very serious consequences and extend potentially through the whole body.
胚胎是位于生命的单个或少数细胞阶段，任何脱靶效应都会造成非常严重的后果，并有可能扩展到全身。

Gene editing is a technique that can result in off-target mutations that can themselves cause genetic problems early and later in life, including cancer.
基因编辑本身是实验性的，并且还会带来脱靶突变，因此它可能在生命的早期或晚期引起遗传问题，包括癌症。

Gene editing is considered experimental and is still linked with off-target mutations, causing genetic problems early and later in life, including the development of cancer.
基因编辑本身是实验性的，它仍然与非靶向突变有关，能够在生命的早期和晚期造成遗传问题，包括癌症的发展。

Gene-editing is still experimental and is associated with off-target mutations, capable of causing genetic problems early or later in life, including the development of cancer.
基因编辑本身是实验性的，它仍然与非靶向突变有关，能够在生命的早期和晚期造成遗传问题，包括癌症的发展。