Examples of using Post-natal development in English and their translations into Croatian
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Effects on post-natal development.
No studies have been conducted with respect to parturition or peri/post-natal development.
Pre- and post-natal development.
Animal studies performed in rats did not indicate harmful effects on parturition,embryonal/foetal and post-natal development.
Peri- and Post-Natal Development.
This study did not indicate direct or indirect harmful effects with respect to fertility, pregnancy, embryonal/fetal development, parturition or post-natal development.
It caused a delay in post-natal development safety margin of 1.
Post-natal development assessment of animals treated prenatally presented decreased glucose tolerance and insulin sensitivity, behavioural alterations and decrease in brain and body weight.
No effects were detected in the post-natal development of rat pups.
No disturbance of post-natal development and reproductive performance was seen in animals exposed during lactation.
Animal studies to determine the effects of bortezomib on parturition and post-natal development were not conducted see section 5.3.
No adverse effects on female reproduction and post-natal development in rats were seen at systemic exposures up to 2,300 times human exposures at the maximum recommended intrathecal dose.
Data from the literature also indicate that decitabine has adverse effects on all aspects of the reproductive cycle, including fertility, embryo-foetal development and post-natal development.
Fertility, pre-natal development and post-natal development were unaffected in rats at doses up to 250 mg/kg/day.
Experimental animal studies are insufficient to assess the safety with respect to fertility, reproduction, development of the embryo or foetus, the course of gestation,and peri- and post-natal development.
The potential effects of plerixafor on male and female fertility and post-natal development have not been evaluated in non-clinical studies.
In the rat peri- and post-natal development study with tafamidis, decreased pup survival and reduced pup weights were noted following maternal treatment during pregnancy and lactation at doses of 15 and 30 mg/kg.
Amifampridine had no adverse reaction on male or female fertility in rats at dosesup to 75 mg/kg/day, and no effect on post-natal development or fertility was observed in the offspring of the treated animals.
Pregnancy: Evaluation of experimental animal studies does not indicate direct or indirect harmful effects with respect to the development of the embryo or foetus,the course of gestation and peri- and post-natal development.
No studies on fertility, early embryonic and post-natal development, or carcinogenicity studies were conducted because chronic dosing in animals would be expected to be associated with development of neutralising antibodies to the human protein.
However, irreversible defects in growing teeth and premature closure of the femoral epiphyseal plate, observed in rat toxicity studies at clinically relevant exposures, represent risks to post-natal development.
In the pre- and post-natal development study in rats, there were no undesirable effects on pregnancy, parturition or lactation of F0 female rats at maternally non-toxic doses(10 and 20 mg/kg/day) and no effects on the growth, development, neurobehavioral or reproductive function of the offspring F1.
Animal studies with H5N1 strain vaccines(A/Vietnam/1203/2004 and A/Indonesia/05/2005) do not indicate direct or indirect harmful effects with respect to fertility, pregnancy, embryonal/fetal development, parturition or post-natal development see section 5.3.
Studies carried out in rats did not reveal significant findings on fertility, embryo-fetal development or pre- and post-natal development at any of the tested doses corresponding to a systemic exposure in rats similar or lower than that observed in humans at the recommended dose of 150 mg once daily.