Examples of using Peg intron in English and their translations into Danish
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Peg Intron Cm ax and AUC measurements increase in a dose-related manner.
This study showed that Peg Intron was superior to interferon alfa-2b Table 5.
Renal clearance appears to account for 30% of total clearance of Peg Intron.
Discontinuation of Peg Intron should be considered in patients who develop new or worsening ophthalmological disorders.
Neutrophil and white cell count reductions at the end of week 4 correlated with the dose of Peg Intron.
Hold the Peg Intron pre-filled pen with your fingers wrapped around the pen body barrel and your thumb on the dosing button figure 7.
Both the Metavir score andIshak grade decreased among subjects treated with Peg Intron in combination with ribavirin.
Combination treatment Peg Intron, when given with ribavirin capsules, is usually given at a dose of 1.5 microgram/kg once a week.
These adverse reactions were common(≥1/100 to< 1/10) in clinical trials in patients treated with Peg Intron monother apy.
Your doctor has prescribed Peg Intron specifically for you and your current condition; do not share this medicine with anyone else.
Dental and gum disorders, which may lead to loss of teeth,have been reported in patients receiving Peg Intron and ribavirin combination therapy.
Mean(SD) Peg Intron elimin ation half-life is approximately 40 hours(13.3 hours), with apparent clearance of 22.0 ml/hr·kg.
There were some cases of more severe neutropenia in patients treated with the recommended doses of Peg Intron in combin ation with ribavirin WHO grade 3.
Following single doses of Peg Intron between 0.25 and 2.0 micrograms/kg/week, serum neopterin concentration was increased in a dose- related manner.
These findings may partly relate to improved metabolic capacity due to reduced hepatic inflammation in patients undergoing treatment with Peg Intron.
The use of Peg Intron in combination with ribavirin had no observable negative impact on the control of HIV viraemia during therapy or follow-up.
However, response rates in this trial were shown to be dependent also on the dose of ribavirin administered in combination with Peg Intron or interferon alfa-2b.
Treatment with Peg Intron in combination with ribavirin was associated with decreases in absolute CD4+ cell counts within the first 4 weeks without a reduction in CD4+ cell percentage.
Haematological abnormalities were more frequently reported in patients receiving Peg Intron in combination with ribavirin when compared to patients receiving interferon alfa-2b in combination with ribavirin.
Peg Intron clinical trials- Naïve patients Two pivotal trials have been conducted, one(C/I97-010) with PegIntron monotherapy; the other(C/I98-580) with PegIntron in combination with ribavirin.
Results from a multiple-dose probe study assessing P450 substrates in chronic hepatitis C patients receiving once weekly Peg Intron(1.5 µg/kg) for 4 weeks demonstrated an increase in activity of.
Caution is therefore advised when Peg Intron treatment is initiated for chronic hepatitis in patients treated with medication with a narrow therapeutic window and sensitive to mild metabolic impairment of the liver.
Please refer to the respective Summary of Product Characteristics of the antiretroviral medicinal products that are to be taken concurrently with HCV therapy for awareness and management of toxicities specific for each product andthe potential for overlapping toxicities with Peg Intron and ribavirin.
Please refer to the respective Summary of Product Characteristics of the antiretroviral medicinal products that are to be taken concurrently with HCV therapy for awareness and management of toxicities specific for each product andthe potential for overlapping toxicities with Peg Intron in combination with ribavirin.