Examples of using P-gp substrate in English and their translations into Dutch
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Medicine
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Colloquial
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Official
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Ecclesiastic
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Financial
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Computer
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Ecclesiastic
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Official/political
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Programming
P-gp substrates or weak inhibitors.
Effects of afatinib on P-gp substrates.
P-gp substrates or weak inhibitors.
Effect of fidaxomicin on P-gp substrates.
The effects of the P-gp substrates are unlikely to have any clinical consequences.
Based on an in vitro study tigecycline is a P-gp substrate.
Lomitapide is not a P-gp substrate but does inhibit P-gp. .
Ticagrelor as well as the active metabolite are P-gp substrates.
Effect of ticagrelor on other P-gp substrates has not been studied.
other metabolites are P-gp substrates.
Results in vivo with the P-gp substrate fexofenadine were inconclusive.
Akynzeo is unlikely to interact with medicinal products which are P-gp substrates.
Therefore, concomitant treatment with other P-gp substrates could lead to enhanced toxicity.
Isavuconazole may increase the exposure of medicinal products that are P-gp substrates.
Therefore, concomitant treatment with other P-gp substrates could lead to enhanced toxicity.
Other P-gp substrates for which a dose reduction may be considered include ticagrelor and dabigatran-etexilate.
Mirabegron increased Cmax and AUC by 29% and 27%, respectively, of the P-gp substrate digoxin in healthy volunteers.
Concomitant administration of the P-gp substrate dabigatran etexilate may result in increased dabigatran plasma concentrations.
and digoxin a P-gp substrate.
Simultaneous administration of ulipristal acetate and a P-gp substrate has not been studied
does not result in clinically relevant increases in concentrations of digoxin(a P-gp substrate), with an 11% increase in plasma AUC.
Therefore, concomitant use of lumacaftor/ivacaftor with P-gp substrates(e.g., digoxin)
Co-administration of digoxin, a P-gp substrate, with empagliflozin resulted in a 6% increase in AUC
In a study performed in healthy volunteers, netupitant does not affect the exposure of digoxin, a P-gp substrate, whereas it increases its Cmax by fold 90%CI 0.9-1.31.
After a single 0.25 mg dose of digoxin, a P-gp substrate, concomitant administration of 127 mg twice daily doses of eliglustat resulted in a 1.7-
dasabuvir are in vitro inhibitors of P-gp, no significant change was observed in the exposure of the P-gp substrate digoxin when administered with Viekirax and dasabuvir.
Cmax for digoxin(P-gp substrate) were increased by 23%
digoxin(a P-gp substrate) or warfarin(S-warfarin,
In vitro results showed for avanafil a modest potential for acting as P-gp substrate and P-gp inhibitor with digoxin as a substrate at concentrations lower than the calculated intestinal concentration.
1.5 hour before administration of the P-gP substrate fexofenadine(60 mg)