Examples of using The steady-state in English and their translations into Finnish
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Medicine
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The steady-state volume of distribution is 0.1 l/kg.
Varenicline did not alter the steady-state pharmacokinetics of digoxin.
The steady-state response usually occurs within a month.
One study in cystic fibrosis patients gives the steady-state volume of distribution as 0.09 l/kg.
The steady-state response usually occurs within a month.
Co-administration with 5 mg linagliptin did not alter the steady-state pharmacokinetics of levonorgestrel or ethinylestradiol.
The steady-state volume of distribution(Vss) is approximately 1.1 i/ kg.
Distribution Following intravenous administration the steady-state volume of distribution of tenofovir was estimated to be approximately 800 ml/ kg.
The steady-state volume of distribution(Vss) is estimated to be 163 litres.
APTIVUS, co-administered with low dose ritonavir, does not substantially affect the steady-state pharmacokinetics of fluconazole.
The steady-state volume of distribution of montelukast averages 8-11 liters.
The steady-state volume of distribution of sugammadex is approximately 11 to 14 litres.
After repeated subcutaneous administration of 40 mg once daily and 1.5 mg/kg once daily regimens in healthy volunteers, the steady-state is reached on day 2 with an average exposure ratio about 15% higher than after a single dose.
The steady-state volume of distribution is 1.1 to 2.1 L/kg after intravenous administration.
In a trial where HIV-infected subjects(n=22)were instructed to take atazanavir 300 mg with cobicistat 150 mg once daily with food, the steady-state atazanavir Cmax, AUCtau and Ctau(mean SD) values were 3.9± 1.9 μg/ml, 46.1± 26.2 μg•hr/ml and 0.80± 0.72 μg/ml.
The steady-state volume of distribution based on plasma concentrations is approximately 1,300 L healthy subjects.
In studies where tipranavir co-administered with low-dose ritonavir was used with or without enfuvirtide,it has been observed that the steady-state plasma tipranavir trough concentration of patients receiving enfuvirtide were 45% higher as compared to patients not receiving enfuvirtide.
The steady-state volume of distribution based on plasma concentrations is approximately 1300 l healthy subjects.
In one pharmacokinetic study the steady-state exposure in poor metabolisers was 164% and 99% higher during treatment with 7.5 mg and 15 mg once daily.
The steady-state volume of distribution based on plasma concentrations is approximately 1300 l healthy subjects.
By contrast, evaluation of the steady-state plasma tipranavir trough concentrations at 10-14 h after dosing from the RESIST-1 and RESIST-2 studies demonstrate that females generally had higher tipranavir concentrations than males.
The steady-state trough concentrations of fulvestrant in children in this study were consistent with that in adults see section 5.2.
The steady-state pharmacokinetic parameters of darunavir were comparable when boosted with cobicistat versus ritonavir.
Distribution The steady-state volume of distribution of nateglinide based on intravenous data is estimated to be approximately 10 litres.
The steady-state pharmacokinetic parameters of atazanavir were comparable when boosted with cobicistat versus ritonavir see Table 4.
The steady-state exposure of ivacaftor is lower than that of Day 1 due to the CYP3A induction effect of lumacaftor see section 4.5.
The steady-state plasma clearance of brivaracetam was similar(0.76 ml/min/kg) to young healthy male subjects(0.83 ml/min/kg) see section 4.2.
The steady-state 24-hour urinary glucose excretion was highly dependent on renal function and 85, 52, 18 and 11 g of glucose/day was excreted by subjects with type 2 diabetes mellitus and normal renal function or mild, moderate or severe renal impairment.