Examples of using Aucinf in English and their translations into German
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Medicine
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Colloquial
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Official
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Ecclesiastic
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Financial
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Ecclesiastic
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Political
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Computer
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Programming
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Official/political
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Political
Dose proportionality for Cmax and AUCinf was demonstrated between 0.2 and 1.6 mg/kg.
Co-administration of 200 mg fidaxomicin twice daily with a single dose of 10 mg rosuvastatin to healthy subjects didnot have a clinically significant effect on the AUCinf of rosuvastatin.
The extent of absorption of levodopa(AUCinf) was similar(13% increase) to that observed in the fasted state.
Administration of a single 400/ 100 mg dose of Kaletra tablets under fed conditions(high fat, 872 kcal, 56% from fat) compared to fasted statewas associated with no significant changes in Cmax and AUCinf.
The co-administration of 600 mg ciclosporin decreased the Cmax and the AUCinf of eltrombopag by 39% and 24%, respectively.
Ledipasvir plasma exposure(AUCinf) was similar in patients with severe hepatic impairment and control patients with normal hepatic function.
The co-administration of 200 mg ciclosporin(a BCRP inhibitor)decreased the Cmax and the AUCinf of eltrombopag by 25% and 18%, respectively.
The unbound plasma pasireotide exposure(AUCinf,u) was increased in subjects with renal impairment(mild: 33%; moderate: 25%, severe: 99%, ESRD: 143%) compared to control subjects.
With progressive renal impairment up to and including end-stage renal disease the primary pharmacokineticparameters of teduglutide increased up to a factor of 2.6(AUCinf) and 2.1(Cmax) compared to healthy subjects.
Relative to subjects with normal renal function, velpatasvir AUCinf was 50% higher in subjects with severe renal impairment see section 4.2.
Repeated doses of 960mg BID vemurafenib increased Cmax and AUCinf of a single 2 mg dose of tizanidine(a CYP1A2 sensitive substrate) approximately 2.2-fold(geometric mean ratio, range 0.7-4.9-fold) and 4.7-fold(geometric mean ratio, range 0.9-16-fold).
Compared to subjects with normal hepaticfunction velpatasvir total plasma exposure(AUCinf) was similar in patients with moderate or severe hepatic impairment.