Examples of using Lispro in English and their translations into German
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Insulin lispro rDNA origin.
Its active substance is insulin lispro.
Lispro in Humalog BASAL is available in a suspension together with protamine sulphate.
Humalog contains the active ingredient insulin lispro.
Avoidance of medication errors when using insulin lispro(200 units/ml) in pre-filled pen.
Only certain CE-marked insulin infusion pumps may be used to infuse insulin lispro.
The change means that insulin lispro is absorbed faster by the body than human regular insulin, and can therefore act faster.
Liprolog Pen 100U/ ml solution for injection Insulin lispro rDNA origin.
Humalog Mix25 is a premixed suspension consisting of insulin lispro(fast-acting human insulin analogue) and insulin lispro protamine suspension intermediate acting human insulin analogue.
The proportion of patients achieving HbA1c<7% was 47.9% with immediate-release exenatide and 42.8% with insulin lispro.
Humalog Mix25 100 U/ ml suspension for injection in vial 25% insulin lispro and 75% insulin lispro protamine suspension rDNA origin.
Using Liprolog in an infusion pump• Only certain CE-marked insulin infusion pumps may be used to infuse insulin lispro.
Humalog is a range of solutions andsuspensions for injection that contain the active substance insulin lispro and are supplied in vials, cartridges and prefilled pens Humalog KwikPen.
The adjusted mean change in body weight from baseline at 52 weeks was -1.0 kg forEperzan(N 122) and +1.7 kg for insulin lispro N 141.
Insulin lispro 200 units/ml solution for injection was bioequivalent to insulin lispro 100 units/ml solution for injection after subcutaneous administration of a single 20 unit dose in healthy subjects.
Clinical trials in patients with type 1 andtype 2 diabetes have demonstrated a reduced number of episodes of nocturnal hypoglycaemia with insulin lispro compared to soluble human insulin.
Insulin lispro is available as Humalog in the soluble form, which acts more or less immediately after injection, and as Humalog Basal in the‘protamine suspension' form, which is absorbed much more slowly so that it works for longer.
In patients who completed the study(52 weeks), the adjusted mean change in baseline in HbA1c was -1.0% for Eperzan(N 121)and -0.9% for insulin lispro N 141.
The time course of insulin lispro action may vary in different individuals or at different times in the same individual and is dependent on dose, site of injection, blood supply, temperature and physical activity.
Clinical trials have been performed in children(61 patients aged 2 to 11) and children and adolescents(481 patients aged 9 to 19 years),comparing insulin lispro to human soluble insulin.
Insulin lispro is available as Liprolog in the soluble form, which acts more or less immediately after injection, and as Liprolog Basal in the‘ protamine suspension' form, which is absorbed much more slowly so that it works for longer.
Results at 26 weeks in a study comparing Eperzan 30 mg SC weekly(with optional uptitration to 50 mg weekly)to prandial insulin lispro as add-on therapy in patients inadequately controlled on insulin glargine alone.
The active substance in Humalog, insulin lispro, is produced by a method known as‘recombinant DNA technology': it is made by bacteria into which a gene(DNA) has been introduced, which makes them able to produce insulin lispro.
Eperzan was more effective than placebo at reducing HbA1c levels when used alone, and was more effective than the diabetes medicines sitagliptin and glimepiride and comparable toinsulin glargine and insulin lispro when used as add-on to other treatments.
As with all insulin preparations, the time course of insulin lispro action may vary in different individuals or at different times in the same individual and is dependent on dose, site of injection, blood supply, temperature and physical activity.
Further in this leaflet it tells you how to deal with mild hypoglycaemia(see Section 3: If you take more Humalog than you need). if you are allergic(hypersensitive)to insulin lispro or any of the other ingredients of this medicine listed in section 6.
In a 24-week study, where either insulin lispro protamine suspension or insulin glargine was added to existing therapy of immediate-release exenatide and metformin, metformin and sulphonylurea or metformin and pioglitazone, HbA1c was lowered by 1.2%(n=170) and by 1.4%(n=167) respectively from a baseline of 8.2.
In this study, patients on 1 or 2 insulin injections per day prior to study entry, discontinued their prestudy insulin regimen and were randomised to dulaglutide once weekly or insulin glargine once daily,both in combination with prandial insulin lispro three times daily, with or without metformin.