Examples of using Nnrtis in English and their translations into German
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Medicine
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Colloquial
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Official
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Ecclesiastic
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Financial
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Ecclesiastic
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Political
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Computer
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Programming
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Official/political
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Political
Other NNRTIs.
Non-nucleoside reverse transcriptase inhibitors NNRTIs.
Combining two NNRTIs has not been shown to be beneficial.
NRTIs and NNRTIs.
VIRAMUNE belongs to the class of non-nucleoside reverse transcriptase inhibitors NNRTIs.
NNRTIs other than rilpivirine(efavirenz, etravirine and nevirapine) are contraindicated see section 4.3.
Raltegravir/ Efavirenz(400 mg single dose/-) NRTIs and NNRTIs.
NNRTIs: careful monitoring for any occurrence of drug toxicity and/or lack of anti-viral efficacy, and dose adjustment if required.
It is not recommended to co-administer rilpivirine with other NNRTIs.
Patients who discontinued treatment with other NNRTIs due to rash may be at higher risk of developing rash during treatment with efavirenz.
Voriconazole may also inhibit the metabolism of NNRTIs besides efavirenz.
Viral isolates recovered from PBMCs of patients enrolled in efavirenz clinical studies who showed evidence of treatment failure(viral load rebound)were assessed for susceptibility to NNRTIs.
Rapid emergence of HIV-strains which are cross-resistant to NNRTIs has been observed in vitro.
Both arms used an Optimised Background Regimen(OBR)consisting of at least 2 antiretrovirals NRTIs with or without NNRTIs.
It is not recommended to combine EDURANT withother non-nucleoside reverse transcriptase inhibitors(NNRTIs) such as delavirdine, efavirenz, etravirine, and nevirapine.
Key drug interactions:It's not recommended that rilpivirine be used in combination with other NNRTIs.
The double non-nucleoside study 2 NN was a randomised, open-label,multicentre prospective study comparing the NNRTIs nevirapine, efavirenz and both medicinal products given together.
Study ACTG 364 enrolled 196 patients who hadbeen treated with NRTIs but not with PIs or NNRTIs.
For those patients failing therapy with Eviplera andwho developed resistance to Eviplera cross resistance to other approved NNRTIs(etravirine, efavirenz, nevirapine) was generally seen.
Time to emergence of nevirapine resistance in cell culture was not altered whenselection included nevirapine in combination with several other NNRTIs.
Darunavir showed synergistic antiviral activity when studied in combination with the protease inhibitors ritonavir, nelfinavir, or amprenavir and additive antiviral activity when studied in combination with the protease inhibitors indinavir, saquinavir, lopinavir, atazanavir, or tipranavir, the N(t)RTIs zidovudine, lamivudine, zalcitabine, didanosine, stavudine, abacavir, emtricitabine,or tenofovir, the NNRTIs nevirapine, delavirdine, or efavirenz and the fusion inhibitor enfuvirtide.
Cross-resistance profiles for efavirenz, nevirapine and delavirdine in vitro demonstrated that theK103N substitution confers loss of susceptibility to all three NNRTIs.
Patients should be carefully monitored for any occurrence of drug toxicity and/ or lack of efficacy during the coadministration of voriconazole and NNRTIs.
Synergistic antiretroviral activity was observed when human T-lymphoid cells infected with the LAI variant of HIV-1 were incubated with indinavir and either zidovudine,didanosine, or NNRTIs.
This indication is based on the results of two 24-week studies of Intelence taken in combination with other anti-HIV medicines including darunavir boosted with ritonavir,which were carried out in patients with virus that was not responding to NNRTIs or protease inhibitors.