Examples of using Rocuronium in English and their translations into German
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Re-administration of rocuronium or vecuronium after sugammadex.
Reversal of neuromuscular blockade induced by rocuronium or vecuronium.
If re-administration of rocuronium or vecuronium is required a waiting time of 24 hours is recommended.
Interactions due to the lasting effect of rocuronium or vecuronium.
Please refer to the package leaflet of rocuronium or vecuronium for a list of the specific medicinal products which potentiate neuromuscular blockade.
Interactions due to the lasting effect of rocuronium or vecuronium.
Although both succinylcholine and rocuronium are used to facilitate emergency department(ED) rapid sequence intubation, the difference in intubation success rate between them is unknown.
Use for reversal of neuromuscular blocking agents other than rocuronium or vecuronium.
Bridion can be used in adults who have received rocuronium and vecuronium, and in children and adolescents who have received rocuronium.
Paralysis may influence intubation success rate in case of the use of succinylcholine and rocuronium.
Sugammadex has not been investigated in patients receiving rocuronium or vecuronium in the ICU setting.
We compared the first-pass intubation success between patients receiving succinylcholine andthose receiving rocuronium.
Time(minutes) from administration of sugammadex at 3 minutes after rocuronium to recovery of the T4/ T1 ratio to 0.9, 0.8 or 0.7.
ED intubations typically entail rapid sequence intubation, with coadministration of a sedative agent and a paralytic medication, however there is also a second way to intubate,i.e. with the use ofsuccinylcholine versus rocuronium.
An additional study looked at the effectiveness of Bridion given after rocuronium in 90 children and adolescents.
It forms a complex with the neuromuscular blocking agents rocuronium or vecuronium in plasma and thereby reduces the amount of neuromuscular blocking agent available to bind to nicotinic receptors in the neuromuscular junction.
Sugammadex can be administered at several time points after administration of rocuronium or vecuronium bromide.
In clinical studies with subjects treated with rocuronium or vecuronium, where sugammadex was administered using a dose labelled for the depth of neuromuscular blockade, an incidence of 0.20% was observed for recurrence of neuromuscular blockade as based on neuromuscular monitoring or clinical evidence.
Time(minutes) from administration of sugammadex or neostigmine at reappearance of T2 after rocuronium or vecuronium to recovery of the T4/T1 ratio to 0.9.
In clinical studies with subjects treated with rocuronium or vecuronium, where sugammadex was administered using a dose labelled for the depth of neuromuscular blockade(N=2,022), an incidence of 0.20% was observed for recurrence of neuromuscular blockade as based on neuromuscular monitoring or clinical evidence see section 4.4.
First-pass intubation successrate was 87.0% with succinylcholine versus 87.5% with rocuronium adjusted odds ratio 0.9; 95% confidence interval 0.6 to 1.3.
Intravenous administration of fusidic acid and high dose flucloxacillin(infusion of 500 mg or more),may cause some displacement of rocuronium or vecuronium from sugammadex.
Bridion was compared with neostigmine(another medicine used to stop the effect ofmuscle relaxants) given after rocuronium or vecuronium in the first study and after cis-atracurium(another muscle relaxant) in the second.
For toremifene, which has a relatively high affinity constant and relatively high plasma concentrations,some displacement of vecuronium or rocuronium from the complex with sugammadex could occur.
Sugammadex should not be used for reversal of neuromuscular blockade induced bysteroidal neuromuscular blocking agents other than rocuronium or vecuronium, since there are no efficacy and safety data for these situations.
For toremifene, which has a relatively high binding affinity for sugammadex and for which relatively high plasma concentrations might be present,some displacement of vecuronium or rocuronium from the complex with sugammadex could occur.
Time(minutes) from administration of sugammadex orneostigmine at deep neuromuscular blockade(1-2 PTCs) after rocuronium or vecuronium to recovery of the T4/ T1 ratio to 0.9.
The incidence of any adverse event was also comparable between these agents:14.7% for succinylcholine versus 14.8% for rocuronium adjusted odds ratio 1.1; 95% confidence interval 0.9 to 1.3.