Examples of using Seroconversion in English and their translations into German
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Seroconversion/ Significant increase rate GMR.
Serology(%) HBeAg loss/ seroconversion.
Seroconversion/ Significant increase rate GMTR.
Uniformly high(97.9% to 99.8% across all studies), seroconversion has not been shown to correlate well with protection.
Seroconversion by ELISA and PRNT were as follows.
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However, in field studies 10% ofsero-negative dogs did not show seroconversion(> 0.1 IU/ml) 3-4 weeks after single primary vaccination against rabies.
Seroconversion to all four antigens occurred in more than 96% of the subjects.
In HBeAg negative paediatric patients, treatment should be administered until HBs seroconversion or there is evidence of loss of efficacy.
Patients with sustained HBeAg seroconversion had a mean HBV DNA of 3.3 log10 copies/ml; and 73.7% had HBV DNA< 4 log10 copies/ml.
Murine Effective Dose 63: vaccination of mice with 0.2 ml of a 5-folddiluted vaccine by subcutaneous route induces seroconversion in at least 63% of the animals.
These studies also established that seroconversion in response to vaccination against measles, mumps, and rubella paralleled protection from these diseases.
Serological tests detect IgM in theacute phase of the disease and IgG seroconversion 7-14 days following the onset of symptoms.
Seroconversion rates in Vaccinia-naïve individuals were defined as appearance of antibody titers equal or greater than the assay cut-off value following receipt of two doses of IMVANEX.
Twenty-one days after the first and second dose of the vaccine, the seroprotection rates, seroconversion rates and seroconversion factors for anti-haemagglutinin(anti-HA) antibody were as follows.
Seroconversion negative pre-vaccination HI titer and post-vaccination HI titer≥ 40; Significant increase positive pre-vaccination HI titer and at least a 4-fold increase in post-vaccination HI titer.
Twenty-one days after the first and second dose of the vaccine, the seroprotection rate, the seroconversion rate and seroconversion factor for anti-haemagglutinin(anti-HA) antibody were as follows.
The seroprotection rate*, seroconversion rate* and the seroconversion factor** for anti-HA antibody to H5N1 A/Vietnam/1194/2004 in the adults measured by SRH assay was as follows.
The immunogenicity 21 days after each half-dose(0.25 ml) of HUMENZA in term of the seroprotection rate, the seroconversion rate and the seroconversion factor, using HI method, were as follows.
Direct antiglobulin test(Coombs test) seroconversion and potential risk of haemolytic anaemia The development of a positive direct antiglobulin test(DAGT) may occur during treatment with cephalosporins.
However, when the monovalent hepatitis A and hepatitis B vaccines were administered concomitantly with specific immunoglobulins, no influence on seroconversion was observed although it may result in lower antibody titres.
However, the proportions of subjects who achieved HBeAg seroconversion at week 48 were similar(11%) between the placebo arm and the adefovir dipivoxil 10 mg arm in adolescent patients.
Telbivudine-treated patients who achieved undetectable HBV DNA by PCR by week 24 had the highest rates of HBV DNA undetectability andHBeAg seroconversion(in HBeAg-positive patients), and the lowest overall rates of virological breakthrough at week 104.
In the consistency study the seroprotection rate, seroconversion rate and seroconversion factor for anti- haemagglutinin(anti-HA) antibody against A/ Indonesia/ 5/ 2005 at 21 days after the second dose were as follows.
The magnitude of the immune response to the seasonal influenza vaccine, and proportion of patients with seroconversion and seroprotection were consistent with those observed in healthy volunteer populations.
Seroprotection HI titre≥ 40** Seroconversion negative pre-vaccination HI titre and post vaccination HI titre≥ 40, Significant increase positive pre-vaccination HI titre and at least a 4-fold increase in post-vaccination HI titre GMTR.
Of those HBeAg-positive subjects, 95% achieved non-detectable HBV DNA,39% achieved HBeAg seroconversion, 90% achieved ALT normalisation at week 52 and 0.5% exhibited resistance at week 48.
The majority of naturally acquired infections is subclinical;however, seroconversion still occurs. When clinical symptoms appear, they vary in type and severity: fever, depression anorexia and peripheral oedema, conjunctivitis(“pink eye”), urticaria and abortion. In young animals, pneumonia and pneumoenteritis may also be seen. The virus is mainly transmitted through semen.
Across all three influenza strains, for the egg-derived vaccineseroprotection rates ranged between 85% and 98%, seroconversion or significant increase rates ranged between 62% and 73% and GMRs ranged between 5.52- and 8.76-fold over baseline HI titers.
The Kaplan-Meier estimates of the proportion of patients who maintained HBeAg seroconversion for at least 52 weeks following treatment discontinuation were 86.2% for telbivudine and 92.8% for lamivudine.
Across all three influenza strains, for the comparator intramuscular vaccine seroprotection rates ranged between 74.8% and95.4%, seroconversion or significant increase rates ranged between 56.4% and 69.3% and GMTRs ranged between 6.63 and 11.2-fold over baseline HI titres.