Examples of using Diffuse large in English and their translations into Japanese
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Diffuse large B-cell lymphoma: 2.6%.
Therapy is usually modeled after the treatment of comparably staged diffuse large cell lymphomas.
Diffuse large B-cell lymphoma Newly diagnosed Surgery(for stage I and II only).
Patients are managed like others with diffuse large cell lymphoma and require doxorubicin-based combination chemotherapy.
Diffuse large B cell lymphomas(DLBCLs) represent a common form of non-Hodgkin's cancer of the blood.
The treatment of Burkitt andBurkitt-like lymphoma/leukemia is the same as treatment for diffuse large B-cell lymphoma.
The incidence of diffuse large B-cell lymphoma increases with age in both males and females.
The new therapeutic approach represented by CAR-T hasgiven a fundamental turning point in the field of diffuse large cell lymphomas.
Most children have diffuse large B-cell lymphoma, although other histologies can be observed.
The following studies established R-CHOP as thestandard regimen for newly diagnosed patients with diffuse large B-cell lymphoma(DLBCL).
The treatment of recurrent diffuse large B-cell lymphoma is the same as the treatment of recurrent Burkitt and Burkitt-like lymphoma/leukemia.
Standard treatment options for Burkitt and Burkitt-like lymphoma/leukemia and diffuse large B-cell lymphoma are described in Table 5.
There are three subtypes of diffuse large B cell lymphoma, of which the activated B cell-like(ABC) form has the poorest three-year survival outcome of 40 percent.
The mature B-cell lymphomas include Burkitt andBurkitt-like lymphoma, diffuse large B-cell lymphoma, and primary mediastinal B-cell lymphoma.
Diffuse large B-cell lymphoma in children and adolescents differs biologically from diffuse large B-cell lymphoma in adults in the following ways.
Therapy is modeled after the treatment of comparably staged diffuse large cell lymphomas, but the optimal approach remains to be defined.
Diffuse large B-cell lymphoma Mature B cell Nodal, abdominal, bone, primary CNS(when associated with immunodeficiency), mediastinal No consistent cytogenetic abnormality identified.
Mature B-cell NHL: Burkitt and Burkitt-like lymphoma/leukemia, diffuse large B-cell lymphoma, and primary mediastinal B-cell lymphoma.
Diffuse large B-cell lymphoma: Cell surface markers are similar to the ones seen in diffuse large B-cell lymphoma, such as CD19, CD20, CD22, CD79a, and PAX-5.
An International Prognostic Index(IPI) for aggressive NHL(diffuse large cell lymphoma) identifies five significant risk factors prognostic of OS:[10].
Unlike mature B-lineage NHL seen in adults, there is no difference in outcome based on histology(Burkitt orBurkitt-like lymphoma/leukemia or diffuse large B-cell lymphoma).
Run into the middle section of the road because of icy waterways,water diffuse large in again on the ice, scuttling up the ice really cost us a lot of time.
The COG conducted a study of 20 patients(14 of whom had Burkitt lymphoma/leukemia)using R-ICE to treat relapsed/refractory B-cell NHL(Burkitt lymphoma/leukemia and diffuse large B-cell lymphoma).
Patients who develop an aggressive high-grade non-Hodgkin lymphoma,usually diffuse large B-cell lymphoma and termed a Richter transformation, have a poor prognosis.
Standard treatment for diffuse, small, noncleaved-cell/Burkitt lymphoma is usually with aggressive multidrug regimenssimilar to those used for the advanced-stage aggressive lymphomas(such as diffuse large cell).
Primary mediastinal B-cell lymphoma, previously considered a subtype of diffuse large B-cell lymphoma, is now a separate entity in the most recent WHO classification.
A subset of pediatric diffuse large B-cell lymphoma cases were found to have a translocation that juxtaposes the IRF4 oncogene next to one of the immunoglobulin loci and has been associated with favorable prognosis compared with diffuse large B-cell lymphoma cases lacking this finding.[14].
Primary mediastinal B-celllymphoma was previously considered a subtype of diffuse large B-cell lymphoma, but is now a separate entity in the most recent World Health Organization(WHO) classification.
No difference using either autologous or allogeneic donor stem cell sources,with 2-year EFS of 50% for diffuse large B-cell lymphoma and 30% for Burkitt lymphoma/leukemia patients who survived to have a transplant.
Patients with aggressive stage I or contiguous stage II diffuse large B-cell lymphoma are candidates for combination chemotherapy with or without involved-field radiation therapy(IF-XRT).