Examples of using Gene function in English and their translations into Portuguese
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Single-gene knockout mutants are being used to examine gene function.
Biotin regulates the gene function, which is crucial for the metabolism.
Contributions to current problems in human genetics: gene function and epigenetic….
Mutations with loss of Nav1.7 gene function were also identified in patients with congenital insensitivity to pain.
Genetically modified mice have been particularly useful in determining gene function.
It is important to study DNA to establish gene function and the effect of mutations on disease.
Sequence homology is an indication of the genetic relatedness of different organisms and gene function.
Biologically, a thorough characterization of its gene function would result in deeper understanding of fruit formation.
Existing data on the sugarcane transcriptome will be integrated to validate gene models and infer gene function.
SNPs in the coding andpromoter regions are more likely to alter gene function and, consequently, the formed protein.
The ability to partially reduce gene function has allowed the study of genes that are lethal when completely knocked out.
The data shown in this paper include allele frequencies of known polymorphic genes in innate and acquired immunity,the majority with proven impact on gene function.
This approachallows for a reliable method to investigate gene function in the retina with a typically higher success rate compared to electroporations in ovo.
But our study shows the same thing to be true with fathers- his lifestyle, and how old he is,can be reflected in molecules that control gene function,” Kitlinska said.
Live computing Biologist Rafael Silva Rocha of the FMRP-USP is studying the gene function of bacteria through the lens of computing rather than molecular biology.
By modifying an organism to express microRNA targeted to its endogenous genes, researchers have been able to knockout orpartially reduce gene function in a range of species.
RNAi in mammals To analyze the gene function in any empirical system, RNAi is used to eliminate expression of the specific genes and observe the resulting effects.
The search for new chemotherapy targets against parasitic disease faces a number of challenges as the lack of tools that enable the study of essential gene function in parasites.
To facilitate the future interpretation of human gene function, the Human Genome Project is also conducting parallel studies on the genetic makeup of other organisms.
He spent three months on the team led by Nora Calcaterra of the National University of Rosário(Argentina), former partner of the center at USP,where he used zebrafish in studies about gene function.
However, the investigation of in vivo gene function by genetic analysis is impaired due to availability of very limited genetic manipulation systems for this organism.
The great potential of RNAi has resulted in successful strategies for silencing a wide variety of protein-coding genes, providing important information about gene function and coded proteins.
Since then, the tool has been applied in basic research to study gene function, and is seen as promising in the field of medicine for the treatment of genetic diseases see Pesquisa FAPESP issue no. 133.
These developments have led to a widespread use of conditional mutagenesis in biomedical research,spanning many disciplines in which it becomes a powerful platform for determining gene function in specific cell types and at specific developmental times.
The aims of this study were:to characterize tcp5 gene function in arabidopsis thaliana floral development, through the study of its expression pattern and morphological characterization of transgenic plants with differential expression of the gene. .
However, two other specific dinucleotides were hypermethylated in the offspring whose dams received higher doses of folic acid, which suggests that increased maternal folic acid intake can cause subtle effects, butmay still alter gene function.
Genetic transformation via agrobacterium with the use of model plants has been an alternative for checking the gene function in response to pathogens, because these model plants have as characteristic a short life cycle and high power of regeneration.
Since the xv century, animals are used routinely in research, mainly for diseases studies, and nowadays the most used animal model is the mouse, which one has more than 90% of participation in researches around the world andit is considered the first track to define gene function in mammals.
The studies about genetic regulation and gene function are very important, since these determine plant development and stress response, and its understanding helps crop management and the obtaintion of superior genotypes with more favorable characteristics.
Zebrafish is a well-established genetic model for both forward(ENU mutagenesis) and reverse(Tilling, zinc finger nuclease targeted knock-out, morpholino knockdown)genetic approaches3,4, while gene function in zebrafish embryos can also be easily blocked or activated using selective pharmacological compounds specific for the encoded products.