Examples of using Lung function decline in English and their translations into Portuguese
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Smoking is associated with evidence of mild obstruction and accelerates lung function decline in adolescents.
It would be useful to identify additional factors that might help predict lung function decline in the early stages of CF, given that, in many cases, FEV1 becomes abnormal only in the advanced stages of the disease.
The fev1postbd is the most reproducible parameter of lung function andshall be used in lung function decline evaluation.
Longitudinal studies of the role that a higher level of objectively measured PADL has in preventing lung function decline in smokers could contribute to preventing smoking-related complications, which consume a significant proportion of health care resources in Brazil and the world.
Although pulmonary function test results can be normal,variable and progressive lung function decline can occur over time.
This improvement or maintenance of VEF1 values confirms other findings showing the advantages of early introduction of dornase alfa for patients with mild disease VEF1>80% in the reduction of lung function decline rate.
It is known that an important aspect of CF evolution andprognosis is the rate of lung function decline, and slowing this rate is crucial for long-term survival.
Smoking is also associated with dysregulation of gene expression in the small airway epithelium and accelerates the aging of the airways,as well as being the principal factor responsible for progressive lung function decline.
Physical activity can prevent COPD regardless of smoking.The biological plausibility of the influence of physical activity on lung function decline relies on the anti-inflammatory effects of physical activity.
Therefore, the objective of the present study was to determine whether variation in lung function over the course of one year is associated with worse clinical outcomes and lung function decline in subsequent years.
Therefore, diabetes mellitus should be considered a major risk factor for lung function decline and, eventually, COPD.
Our results suggest that there is no association between physical inactivity and lung function in adult smokers, as well as reinforcing the importance of smoking cessation and preventing comorbidities such as diabetes mellitus andarterial hypertension in order to prevent lung function decline and COPD.
According to the aforementioned studies,moderate to high levels of regular physical activity are associated with reduced lung function decline and reduced risk of COPD in smokers.
Garcia-Aymerich et al 2005 followed up 6,790 adults for 10 years to assess the association between physical activity and lung function decline and COPD risk among smokers and nonsmokers.
Why do these SSc patients in Brazil have such rapid decline in lung function?
Early treatment with corticosteroids seems to prevent or ameliorates a decline in lung function.
The rate of decline in lung function has been proposed as a more reliable criterion.
Exercise attenuates the decline in lung function, improves cardiovascular performance, increases functional capacity, and improves quality of life.
Previous studies have found an association between the use of antibiotics and a decline in lung function in patients with CF.
Two drugs, nintedanib and pirfenidone,both of which slow the decline in lung function, were recently approved for the treatment of IPF.
Hypertensive patients are predisposed to left ventricular(lv) remodeling andfrequently exhibit decline in lung function as compared to the general population.
In terms of intergroup analysis, it was evident that irrespective of age,the morbidly obese presented a decline in lung function when compared to the obese.
These findings corroborate those of previous studies showing that pulmonary exacerbations cause a decline in lung function over time and that a decline in FEV1 is associated with the severity of pulmonary exacerbations, requiring hospitalization and intravenous administration of antibiotics.
The biological plausibility of the influence of physical inactivity on the decline of lung function relies on the elevated levels of inflammatory mediators seen in physically inactive subjects.
However, over time, P. aeruginosa strains of the mucoid phenotype, which are associated with a more accelerated decline in lung function and a greater risk of death.
Venners et al. evaluated 1718 children and adolescents andreported a mild association between parental smoking and the decline in lung function of children who were passive smokers.
Other authors have shown that the use of intravenous antibiotics to treat pulmonary exacerbations is a risk factor for the decline in lung function over time in CF patients.
One recent study reported a reduced rate of decline in lung function after laparoscopic fundoplication in lung transplant recipients with GERD.
Studies have shown that AATD can increase the impact of smoking on the lungs, resulting in an increased rate of decline in lung function and early emphysema in smokers.
In addition, daily production of sputum, wheezing, andthe number of lung exacerbations treated with intravenous antibiotics also seem to be related to a decline in lung function among CF patients.