Examples of using Microarrays in English and their translations into Russian
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So, in the first example, DNA was hybridized on microarrays, while RNA was hybridized on hGWSA.
Microarrays can be found at market prices ranging from €60 to €220 each.
The dominant contemporary techniques, microarrays and RNA-Seq, were developed in the mid-1990s and 2000s.
Phycobilisomes can be used in prompt fluorescence, flow cytometry,Western blotting and protein microarrays.
In addition, these microarrays are highly sensitive- they can detect single molecules of protein.
The company's activities include the creation of chips and microarrays to implement them in everyday life.
Agilent microarrays contain 60-nucleotide probes and are hybridized at 60-65 С 29-33.
Diagnostic markers discovering and pathology mechanism elucidation using splicing-sensitive microarrays.
Applying p-values to microarrays is complicated by the large number of multiple comparisons(genes) involved.
Among other research guidelines of the laboratory, there are studies focused on mtDNA recombination andstudies of mtDNA using microarrays.
DNA microarrays are solid surfaces, usually a small chip, to which short DNA polymers of known sequence are covalently bound.
These issues are especially relevant when the number of simultaneoustests can be very large, as is increasingly the case in the analysis of data from DNA microarrays.
Splicing-sensitive Affymetrix microarrays contain 25-nucleotide probes hybridized with a DNA at temperature 45 С 28.
Since the first descriptions in 2006 and2008, RNA-Seq has been rapidly adopted and overtook microarrays as the dominant transcriptomics technique in 2015.
Microarrays require some genomic knowledge from the organism of interest, for example, in the form of an annotated genome sequence, or a library of ESTs that can be used to generate the probes for the array.
Next generation sequencing offers several advantages over microarrays: it has reduced background, increased sensitivity, improved dynamic range and greater density of information.
Biotechnologies include bioprocessing technology, monoclonal antibodies, cell culture, recombinant DNA technology, cloning, protein engineering,biosensors, nanobiotechnology and microarrays.
In 2010 the International Standard Cytogenomic Array Consortium recommended to use microarrays as a first-tier clinical diagnostic test for individuals with congenital anomalies instead of karyotyping 86.
Large-scale investigations using microarrays targeted to exon junctions enabled to determine basic functioning mechanisms of primary splicing factors: SRSF1 and SRSF2[43], PTB[44], hnRNP family 45.
Key experimental techniques in proteomics include 2D electrophoresis, which allows the separation of a large number of proteins, mass spectrometry, which allows rapid high-throughput identification of proteins and sequencing of peptides(most often after in-gel digestion),protein microarrays, which allow the detection of the relative levels of a large number of proteins present in a cell, and two-hybrid screening, which allows the systematic exploration of protein-protein interactions.
Such an ability was developed for DNA chips(oligonucleotide microarrays) which are commonly used in basic and applied research, to monitor the levels of expression of genes, in identifying the functions of genes, assessing genetic variation, and elucidating new targets for therapeutic drugs.
Recognizing that advances in enabling technologies are the result of a convergence of different sciences and technology and are critical for future life sciences research and development, States Parties reviewed a number of relevant, interdependent advances, including: bioinformatics; computational biology;DNA microarrays; gene synthesis technology; high-throughput mass spectrometry; high-throughput sequencing; nanotechnology; synthetic biology; systems biology; and whole-genome directed evolution.
States Parties reviewed various enabling technologies, including, for example, in: bioinformatics; computational biology;DNA microarrays; gene synthesis technology; high-throughput mass spectrometry; high-throughput sequencing; nanotechnology; synthetic biology; systems biology; and whole-genome directed evolution.
Microarray analysis has proved most beneficial in understanding and characterizing this response.
These fragments are hybridized to oligos on the microarray.
One such improvement, ChIP-on-chip(ChIP-chip),combines ChIP with microarray technology.
Archetypal cases for the application of feature selection include the analysis of written texts and DNA microarray data, where there are many thousands of features, and a few tens to hundreds of samples.
A DNA microarray is a collection of microscopic DNA spots(oligonucleotide probes) attached to a solid surface.
The result of this study is a developed technology for peptide microarray data analysis, which may be used to evaluate a large number of samples and a greater number of classes.
Recent examples include work at the Naval Research Laboratory in Washington, D.C.,using Cowpea mosaic virus(CPMV) particles to amplify signals in DNA microarray based sensors.