As patients with severe liver disease were not studied, nateglinide is contraindicated in this group.
Aangezien patiënten met een ernstige leveraandoening niet bestudeerd werden, is nateglinide gecontraïndiceerd bij deze groep.
In vivo, nateglinide has no clinically relevant effect on the pharmacokinetics of medicinal products metabolised by CYP2C9 and CYP3A4.
In vivo heeft nateglinide geen klinisch relevant effect op de farmacokinetische effecten van geneesmiddelen die gemetaboliseerd worden door CYP2C9 en CYP3A4.
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In vitro studies show that nateglinide is extensively bound(97- 99%)
In vitro onderzoeken laten zien dat nateglinide sterk(97- 99%) gebonden is aan serumeiwitten,
No clinically significant differences in nateglinide pharmacokinetics were observed between men and women.
Er zijn geen klinisch significante verschillen waargenomen in de farmacokinetische eigenschappen van nateglinide tussen mannen en vrouwen.
Nateglinide closes ATP-dependent potassium channels in the beta-cell membrane with characteristics that distinguish it from other sulphonylurea receptor ligands.
Nateglinide sluit ATP-afhankelijke kaliumkanalen in het membraan van de bèta-cel op een karakteristieke wijze die zich onderscheidt van andere sulfonylureum receptorliganden.
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Hoe "nateglinide" te gebruiken in een Engels zin
Take nateglinide exactly as your doctor tells you to.
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Nateglinide was developed by the Swiss pharmaceutical company Novartis.
Nateglinide is also sold under the names Nateglinida, Starlix.
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Starlix nateglinide should those listed here variety and production.
Nateglinide belongs to a group of drugs called meglitinides.
Do not take nateglinide if you skip a meal.
Nateglinide belongs to a group of medications called Glinides.
Nateglinide and repaglinide have a similar action to sulfonylureas.
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