Voorbeelden van het gebruik van Ribozymes in het Engels en hun vertalingen in het Nederlands
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Most ribozymes are involved in the processing of RNA.
The methods used to discover artificial ribozymes are based on Darwinian evolution.
Ribozymes are essentially RNA molecules that are capable of catalyzing a chemical reaction.
Self-splicing introns are usually found in RNA molecules that are intended to catalyse biochemical reactions, ribozymes.
The discovery of ribozymes supported the RNA World Hypothesis.
colleagues discovered a class of RNAs that is capable of catalyzing chemical reactions─ ribozymes.
Further examples of ribozymes include the hairpin ribozyme,
structure of these naturally occurring molecules has led to the development of synthetic ribozymes that are made in the laboratory.
In the future, ribozymes may also be used as therapeutic agents in the correction of genetic disorders.
today, many scientists believe that ribozymes are remnants of an ancient world that existed before the evolution of proteins.
Ribozymes are present in the nucleus,
Reverse transcriptase is used to mutate these ribozymes by reverse transcribing them into various cDNA which can then be amplified with mutagenic PCR.
Ribozymes have been extensively investigated by researchers to try
This raises the exciting possibility that artificial ribozymes could be used as a therapeutic agents to target RNA molecules that cause diseases such as HIV.
Ribozymes also play a role in other vital reactions such as RNA splicing,
Also called catalytic RNA, ribozymes are found in the ribosome where they join amino acids together to form protein chains.
Ribozymes exist in nature as catalytic RNA molecules that either aid the hydrolysis of their own phosphodiester bonds
Researchers have developed synthetic ribozymes in the laboratory that are able to catalyze their own synthesis under specific conditions.
Large ribozymes may have up to 3000 nucleotides and can generate reaction products with a free 3'- hydroxyl and 5'-phosphate group.
ISpinach has been used to visualised ribozymes, and it was found that iSpinach is a better contender than Spinach or other DFHBI-binding proteins.
Large ribozymes splice flanking sequences together, while small ribozymes cleave conserved sites that exist within their own molecule.
Examples of small ribozymes include the hammerhead, the hairpin, the hepatitis delta ribozymes and varkud satellite RNA.
These ribozymes exhibit all the same features as a protein enzyme including transition state stabilization,
Catalytic RNA molecules(ribozymes) were discovered in the early 1980s, leading to a 1989 Nobel award to Thomas Cech and Sidney Altman.
Since ribozymes have been discovered, the naturally occurring ribozymes have fallen into two main groups: large ribozymes and small ribozymes.
Many naturally occurring ribozymes either catalyze the hydrolysis of their own phosphodiester bonds
Similar ribozymes are also being made that could be used to break up RNA viruses
Specifically designed ribozymes could potentially be used to shear genes
Although most targets of ribozymes are RNA, evidence suggests that the assembly of amino acids into a protein that occurs during translation is also catalyzed by RNA, meaning the ribosomal RNA itself is also a ribozyme.
In models of such diseases, ribozymes have been successful at achieving this and a ribozyme that has been shown to target
