Примеры использования Adhesion molecule на Английском языке и их переводы на Русский язык
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GC are known to suppress the transcription of adhesion molecule genes.
Activated leukocyte cell adhesion molecule and prognosis in acute ischemic stroke.
Keywords: preeclampsia; hypertension in pregnancy; adhesion molecules.
Cell adhesion molecules allow cells to identify each other and interact.
Another factor possibly affecting adhesion molecule levels is corticosteroid therapy.
The extracellular region contains three Ig-like domains, andnine non-Ig like domains similar to that of neural cell adhesion molecule.
Experimental research has targeted adhesion molecules known as selectins on epithelial cells.
Soluble adhesion molecules are capable of modulating immune response, acting not only as activators but also as immune reaction inhibitors 8, 9.
Therapeutic effects cannot be responsible for the imbalance in adhesion molecule networks in all studied subjects.
The neural cell adhesion molecule(NCAM) was identified as a new GDNF-receptor in neurons 87.
In some cases topical hormones can influence induced cellular adhesion molecule expression in the inflammation focus as well 31.
Soluble differentiating adhesion molecules are formed by the proteolytic shedding of membrane proteins and/or alternative splicing of matrix RNA 2.
However, there are insufficient data in the literature showing the effect of other antibacterial preparations,indicated in COPD exacerbation, on adhesion molecule balance.
In its turn,the imbalance in adhesion molecule networks is associated with bronchial patency impairment.
In our study the frequency of inhalant GC administration was not significantly different in COPD patients of group 2 and3 having differences in soluble adhesion molecule levels.
In recent years, the interrelation between adhesion molecules, inflammation and oxidative stress have been actively discussed.
Smokers with COPD have been previously shown[6, 7] to have alterations in a wide range of soluble differentiating leucocyte molecules, including adhesion molecules.
We have already underlined the decrease in soluble adhesion molecule levels while treating COPD exacerbations with systemic GC and antibiotics 30.
Formation of synapses represents a dynamic process with participation of pre- and postsynaptic cells and a number of factors, receptors,signaling molecules and adhesion molecules.
Peripherin 2 may function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim.
These pathways induce the production of pro-inflammatory cytokines,chemokines and adhesion molecules with the help of transcription factors NF-kB and AP-1 63, 64-66.
Marked decrease in adhesion molecule concentration correlated with a more severe COPD course, as well as more frequent exacerbations, both moderate and severe, requiring antibiotics and systemic GC, or hospitalization.
This great diversity is what allows the GPI proteins to have a wide range of functions including acting as hydrolytic enzymes, adhesion molecule, receptors, protease inhibitor and complement regulatory proteins.
As a result of growing systemic inflammatory reaction, adhesion molecules expression on endotheliocytes and circulating blood cells increases, promoting further activation, mobilization and extravasation of leucocytes 17, 18.
This release of substances promotes chemotaxis of more neutrophils to the site of infection, andglomerular cells can be damaged further by the adhesion molecules during the migration of neutrophils.
Smoking-induced alterations to the network of soluble intercellular adhesion molecules are involved in the formation and progression of chronic inflammation and obstructive disorders in COPD.
In COPD even peroral GC insufficiently inhibit neutrophilous inflammation, cytokine release in the airways andinflammation mediator gene expression(including adhesion molecules), which they silence in normal conditions.
Alterations of adhesion molecule expression by peripheral phagocytes are multidirectional in a number of cases and reflect the peculiarities of pathogenetic mechanisms of developing hypertension in preeclampsia and essential hypertension.
People treated with H1 antihistamines exhibit reduced production of histamine andleukotrienes as well as downregulation of adhesion molecule expression on the vasculature which in turn attenuates allergic symptoms by 40-50.
Although it is identified as a cell adhesion molecule, EpCAM does not structurally resemble any of the four major families of cell adhesion molecules, namely cadherins, integrins, selectins, and members of the immunoglobulin super-family.