Примеры использования Cofactors на Английском языке и их переводы на Русский язык
{-}
-
Official
-
Colloquial
Metal ions are common cofactors.
Cofactors of HPV in cervical oncogênese.
Different tissues use different cofactors.
PSI comprises more than 110 cofactors, significantly more than photosystem II.
Nanoarchaeum cannot synthesize most nucleotides, amino acids,lipids, and cofactors.
The cofactors can be pigments(like chlorophyll, pheophytin, carotenoids), quinones, or iron-sulfur clusters.
Enzymes for ammonia synthesis in nature called nitrogenases are proteins with cofactors that contain Fe or Mo.
It employs two covalently coupled cofactors- an iron sulfur cluster and a siroheme- which deliver electrons to the substrate via this coupling.
There have been reviewed the main approaches to the study of energymetabolism in cancer cells, based on fluorescent imaging of NADH and FAD cofactors.
Cofactors can be either inorganic(e.g., metal ions and iron-sulfur clusters) or organic compounds e.g., flavin and heme.
The protein splicing reactions which are known now do not require exogenous cofactors or energy sources such as adenosine triphosphate(ATP) or guanosine triphosphate GTP.
Some of these cofactors are able to bind to the estrogen receptor/Clomid complex, but others are blocked due to the change in shape.
Iterative Protein Redesign and Optimization(IPRO) redesigns proteins to increase or give specificity to native ornovel substrates and cofactors.
These metals are used in some proteins as cofactors and are essential for the activity of enzymes such as catalase and oxygen-carrier proteins such as hemoglobin.
The estrogen receptor requires binding of an estrogen or drug at its binding site andalso the binding of any of several cofactors at different sites.
This collection of transcription factors, in turn, recruit intermediary proteins such as cofactors that allow efficient recruitment of the preinitiation complex and RNA polymerase.
Cofactors NADH and FAD which are present in the cell in an oxidized(NAD+, FAD) or reduced form(NADN, FADN 2) play the role of electron donors and acceptors in reactions of ATP formation 1-7.
Although only a small percentage of men with varicocele is infertile,varicocele accelerates spermatogenic injury is associated with other cofactors, for example, development of antispermal antibodies.
FLIM provides the possibility to study metabolic cofactors in living cells by measuring mean time spent by the molecule in an excited state and not factual fluorescence intensity.
The nuclear protein binds to a purine-rich sequence known as the PU-box found on enhancers of target genes, andregulates their expression in coordination with other transcription factors and cofactors.
These cofactors play an important role in energy metabolism reactions acting as electron carriers and, being fluorescent, serve as a basis for metabolic process analysis in living cells and tissues without the use of additional coloring agents.
Studying cellular metabolism by fluorescence lifetime imaging(FLIM)is based on the fact that fluorescence lifetime of cofactors NADH and FAD significantly differs depending on whether they are in a free or protein-bound state.
The result is that in some tissues Clomid acts as an antagonist- the cofactor used in that tissue cannot bind and so the receptor remains inactive- and in others Clomid acts as an agonist(activator), because the cofactors used in that tissue are able to bind.
Development of optical visualization technologies has provided the possibility of noninvasive analysis of metabolic cofactors NADH and FAD in living tumor cells at high spatial resolution(up to several hundred nanometers) without using additional coloring agents and with no significant effect on biochemical and physiological condition of cells.
In this ischemic injury example, it appears that hypoxia triggers the response of the injury tissue in the mode of HIF accumulation,which in turn requires cofactors to form a transcriptional complex leading to up-regulation of genes involved in the communication with the remote repair mechanism for the recruitment of repair materials and process.
Annotation arising from the scientific literature includes, but is not limited to: Protein andgene names Function Enzyme-specific information such as catalytic activity, cofactors and catalytic residues Subcellular location Protein-protein interactions Pattern of expression Locations and roles of significant domains and sites Ion-, substrate- and cofactor-binding sites Protein variant forms produced by natural genetic variation, RNA editing, alternative splicing, proteolytic processing, and post-translational modification Annotated entries undergo quality assurance before inclusion into UniProtKB/Swiss-Prot.
More than 300 enzymes require magnesium as cofactor.
TFB uses a zinc ion(Zn2+) as a cofactor and accepts one ion per subunit.
Arylsulfatase A is activated by saposin B(Sap B),a non-enzymatic proteinaceous cofactor.
Glutathione(GSH) participates in leukotriene synthesis and is a cofactor for the enzyme glutathione peroxidase.