Примеры использования Intron на Английском языке и их переводы на Русский язык
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It is located in intron 7.
Many introns appear to be mobile genetic elements.
This gene contains no introns.
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Enhancers can also be found within introns.
The TIMP4 gene is located within an intron of this gene and is transcribed in the opposite direction.
He began his career in 2001 as an economist at Intron.
The RNA components of snRNPs interact with the intron and are involved in catalysis.
Cis-elements may be located in 5' or3' untranslated regions or within introns.
The APOE gene consists of four exons and three introns, totaling 3597 base pairs.
The most stable pattern was revealed for MLL-MLLT10 FG: MLL breakpoints in 4 of 5(80%)cases were found in intron 9.
The primary transcript of this gene contains an intron with two possible acceptor sites.
A spliceosome assembles on an intron, and the snRNP subunits fold the RNA so that the 5' and 3' ends of the intron are joined.
The most common breakpoint position in MLL gene in infants with ALL was intron 11, in AML intron 9.
Pre-miRNAs that are spliced directly out of introns, bypassing the Microprocessor complex, are known as"Mirtrons.
The authors studied the spectrum of Fox target genes, determined the main regulatory cis-element UGCAUG, which is an enhancer orsilencer within downstream or upstream intron, respectively 72, 73.
The gene RELN has many more SNPs among its 65 exons and64 introns,- even in intron 4 there are tens of SNPs.
Recognition of the intron splice sites is mediated by a base-paired secondary structure of the mRNA that forms at the exon/intron boundaries.
This gene consists of 13 exons, andalternatively spliced transcripts containing several intron sequences have been detected, but no isoforms encoded by these transcripts have been identified.
I must say, the success of scientists must not only perseverance, but also elementary luck, for example,successfully selected detergent or that in receptor gene intron was not accidental- cut sections.
Probably, similar to the role of information-RNA and introns are different levels of contexts, that must be somehow"read" and"digested" live cell.
The intron upstream from exon 4 has a polypyrimidine tract that doesn't match the consensus sequence well, so that U2AF proteins bind poorly to it without assistance from splicing activators.
The most common breakpoint location within MLL gene in ALL patients was intron 11, detected in 31 cases(49%), less frequently breakpoints in intron 10(n=13; 21%) and intron 9(n=9; 14%) were found.
Studies of group I introns from Tetrahymena protozoans indicate that some introns appear to be selfish genetic elements, neutral to the host because they remove themselves from flanking exons during RNA processing anddo not produce an expression bias between alleles with and without the intron.
Comparing the exonic structure shown in the first line(green) with the one in the second line(yellow)shows intron retention, whereas the comparison between the second and the third spliceform(yellow vs. blue) exhibits exon skipping.
ALL patients who had breakpoints in intron 11 were significantly younger than all other patients(3,1 vs 5,6 mo p=0,035), mainly due to the difference to intron 9 patients 3,1 vs 6,6 mo p=0,040.
The authors[70, 71] determined the spectrum of ESRP1 and ESRP2 target genes, the key motif of cis-elements- UGG, the principle of splicing regulation:cis-elements in downstream intron lead to exon inclusion, while being within exon, they lead to its skipping.
Targeting some splice targets results in intron inclusions, while activation of cryptic splice sites can lead to partial inclusions or exclusions.
Materials and methods: ultrasonography was performed to determine the status of fetuses andnewborns from 77 pre-eclamptic gravidae with existing deletion of the pair 27 of nucleotides in the intron 4 of the eNOS gene noncoding region, from patients with a normal genotype, and from 20 gravidae of the control group; dopplerometry, cardiotocography, Apgar scoring, incidence, causes of neonatal death.
In an earlier analysis based on nDNA myoglobin intron 2 and GAPDH intron 11 sequence data, the authors found the sapayoa"as a deep branch in the group of broadbills and pittas of the Old World tropics.