Примеры использования Isoform на Английском языке и их переводы на Русский язык
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There are two isoforms of the protein.
Isoform 2(Claudin 18.2) is abundant in gastric tumors.
This enzyme can use many different isoforms of ferredoxin.
Three isoforms of CPT1 are currently known: CPT1A, CPT1B, and CPT1C.
There are four different LTBP isoforms known, LTBP-1, LTBP-2, LTBP-3 and LTBP-4.
Its isoform modulates ezrin, a key protein in the maintenance of cell lamellipoidal extensions.
Cyclooxygenase(COX) has two well-studied isoforms, called COX-1 and COX-2.
The ACE isoforms consisted of one domain were also detected in mammals.
This gene encodes a myosin heavy chain beta(MHC-β) isoform expressed primarily in the heart.
There exist two isoforms of ChAT, both encoded by the same sequence.
There are two alternatively spliced transcript variants of this gene encoding different isoforms.
A third isoform, the brain isoform(CPT1C), was isolated in 2002.
Alternative splicing results in multiple transcript variants encoding different isoforms of the protein.
Furthermore, specific LTBP isoforms have a propensity to associate with specific LAP•TGF-β isoforms. .
Some chromodomain-containing genes have multiple alternative splicing isoforms that omit the chromodomain entirely.
It was discovered that the isoform(a)pro-GDNF is localized in the Golgi apparatus, while the(b)pro-GDNF is associated with the secretory fraction.
Like any other selective COX-2 inhibitor("coxib"),etoricoxib selectively inhibits isoform 2 of the enzyme cyclooxygenase COX-2.
The liver isoform(CPT1A or CPTI-L) is found throughout the body on the mitochondria of all cells except for skeletal muscle cells and brown adipose cells.
Ankyrin has been found to bebounded to βIV spectrin, a spectrin isoform enriched at nodes of Ranvier and axon initial segments.
Paired-end sequencing produces more robust alignments/assemblies,which is beneficial for gene annotation and transcript isoform discovery.
The CPT1 skeletal muscle and heart isoform, CPT1B, has been shown to be 30-100-fold more sensitive to malonyl-CoA inhibition than CPT1A.
This discovery contributed to the molecular identification of K-Cl cotransport(KCC)in human embryonic cells transfected by KCC1 isoform cDNA, 16 years later.
Similarly, another isoform of neuroligin(NLGN2) interacts with gephyrin, a scaffolding protein specific to GABA-ergic synapses, and is responsible for activation of the synaptic adapator protein collybistin.
Although found in many tissues, amylase is most prominent in pancreatic juice and saliva,each of which has its own isoform of human α-amylase.
Isoform Intersa B15 40 capsules Indication: Common and chronic fatigue, liver disorders, athletes, hangover recovery, antioxidant, atherosclerosis and hypertension, tachycardia, cirrhosis and wound healing.
The nucleotide sequence corresponding to the linker region encodes a set of three alternative translation start codons from which the third PAX6 isoform originates.
Since gene regulation may occur at the mRNA isoform level, splice-aware alignments also permit detection of isoform abundance changes that would otherwise be lost in a bulked analysis.
In kidney cancer, this effect could be due to the presence of mutations in the von Hippel-Lindau tumor suppressor gene upregulating glycolytic enzymes,including the M2 splice isoform of pyruvate kinase.
Each glucose transporter isoform plays a specific role in glucose metabolism determined by its pattern of tissue expression, substrate specificity, transport kinetics, and regulated expression in different physiological conditions.
With the accumulation of RNA-seq data that are capable of estimating expression profiles for alternatively spliced isoforms, machine learning algorithms have also been developed for predicting and differentiating functions at the isoform level.