Примери за използване на Advanced fibrosis на Английски и техните преводи на Български
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Medicine
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Ecclesiastic
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Ecclesiastic
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Computer
Experience in CHB patients with advanced fibrosis or cirrhosis.
Patients with advanced fibrosis were assigned to Pegasys treatment(group C, n=10).
One study found out smoking increases insulin resistance and leads to advanced fibrosis.
Fatty liver: Diagnosis of advanced fibrosis from stool microbes shows promise.
There was no difference in response rate between these patients and those without advanced fibrosis or cirrhosis.
A total of 283/ 1351(21%)of patients had advanced fibrosis or cirrhosis, 85/ 1351(6%) had cirrhosis.
The results exceed existing fibrosis scores,accurately identifying 92 per cent of patients with advanced fibrosis.
A new test may soon be available to predict advanced fibrosis in people with non-alcoholic fatty liver disease.
The results exceed the existing fibrosis scores,accurately identifying 92% of patients with advanced fibrosis.
A new test will soon be available to predict advanced fibrosis in people with the non-alcoholic fatty liver disease(NAFLD).
An international research team has developed a PRO-C3 biomarker-based score to accurately predict the presence(or absence) of advanced fibrosis in people with NAFLD.
A higher incidence of anaemia in patients with advanced fibrosis receiving simeprevir in combination with peginterferon alfa and ribavirin has been reported.
For each 67 mg increase in caffeine consumption(about one half cup of coffee)there was a 14% decrease in the odds of advanced fibrosis for patients with HCV.
A total of 151 patients without advanced fibrosis were 2:1 randomized to Pegasys(group A, n=101) or untreated control(group B, n=50), respectively.
The international research team developed a score, based on the PRO-C3 biological marker,to accurately predict the presence(or absence) of advanced fibrosis in people with NAFLD.
In another clinical trial, non-responder patients with advanced fibrosis or cirrhosis(Ishak score of 3 to 6) and baseline platelet counts as low as 50,000/ mm3 were treated for 48 weeks.
The researchers combined this data with routine clinical information- such as age, the presence of diabetes, andplatelet count- to develop a highly accurate tool to detect advanced fibrosis in NAFLD.
Therapeutic guidelines recommend that, in patients with advanced fibrosis and cirrhosis, surveillance for hepatocellular carcinoma should continue even after sustained viral response has been achieved.
Professor George and his team combined this data with routine clinical information- such as age, presence of diabetes, andplatelet count- to develop a highly accurate tool to detect advanced fibrosis in NAFLD.
All(10/10) patients with advanced fibrosis or cirrhosis at baseline(Ishak fibrosis score of 4, 5 or 6) had a≥ 1 point decrease(median decrease from baseline was 1.5 points).
Professor George and his team combined this data with routine clinical information, such as age, the presence of diabetes, and platelet count,to develop a very accurate tool for detecting advanced fibrosis in the non-alcoholic fatty liver.
Associate Professor Eslam added,“Our tool will help identify advanced fibrosis in patients, which is crucial because they are the people most likely to develop future health complications.
Upon the published data for the comparability of FibroSkan in relation to the liver biopsy, there is a good correlation of the results of patients with low fibrosis anda considerate correlation of those with advanced fibrosis, where the percentage would reach 77%.
Associate Professor Eslam added,"Our tool will help identify advanced fibrosis in patients, which is crucial, as these are the people who are most likely to develop future health complications.
Consideration should be given to potentially extending the duration of therapy beyond 12 weeks and up to 24 weeks; especially for those subgroups who have one ormore factors historically associated with lower response rates to interferon-based therapies(e.g. advanced fibrosis/cirrhosis, high baseline viral concentrations, black race, IL28B non CC genotype, prior null response to peginterferon alfa and ribavirin therapy).
In the HALT-C study, patients with CHC and advanced fibrosis or cirrhosis who were non-responders to previous treatment with interferon alfa or pegylated interferon alfa monotherapy or in combination therapy with ribavirin were treated with Pegasys 180 mcg/week and ribavirin 1000/1200 mg daily.
Consideration should be given to treating these patients, and potentially extending the duration of therapy with sofosbuvir, peginterferon alfa and ribavirin beyond 12 weeks and up to 24 weeks; especially for those subgroups who have one ormore factors historically associated with lower response rates to interferon-based therapies(advanced fibrosis/cirrhosis, high baseline viral concentrations, black race, IL28B non CC genotype).
It has been found that they are more informative to the detection of more advanced fibrosis than in the intermediate and early stages of fibrosis, when there is an expectation of better response to therapeutic interventions.
Consideration should be given to treating these patients, and potentially extending the duration of therapy with sofosbuvir, peginterferon alfa and ribavirin beyond 12 weeks and up to 24 weeks; especially for those subgroups who have one or more factors historically associated with lower response rates to interferon-based therapies(prior null response to peginterferon alfa andribavirin therapy, advanced fibrosis/cirrhosis, high baseline viral concentrations, black race, IL28B non CC genotype).
Monitor advanced liver fibrosis in people diagnosed with fatty liver disease.