Примери за използване на Decrease the plasma на Английски и техните преводи на Български
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Letermovir may decrease the plasma concentrations of phenytoin.
Interaction with indinavir/ ritonavir not studied Ritonavir induces glucuronidation andas a result is expected to decrease the plasma concentrations of atovaquone.
Phenytoin and carbamazepine decrease the plasma concentration of topimarate.
Interaction with indinavir/ritonavir not studied Ritonavir induces glucuronidation andas a result is expected to decrease the plasma concentrations of atovaquone.
Letermovir may decrease the plasma concentrations of CYP2C19 substrates.
Co-administration of medicinal products which are inducers of CYP3A4 and/or CYP3A5 may decrease the plasma concentrations of isavuconazole.
St John's wort is expected to decrease the plasma concentrations of darunavir and ritonavir.
Interaction with indinavir/ ritonavir not studied Ritonavir induces oxidation by CYP2C9 and glucuronidation andas a result is expected to decrease the plasma concentrations of anticonvulsants.
St John' s wort is expected to decrease the plasma concentrations of etravirine.
Ritonavir dosed as a pharmacokinetic enhancer or as an antiretroviral agent induces glucuronidation andas a result is expected to decrease the plasma concentrations of atovaquone.
Letermovir may increase or decrease the plasma concentrations of repaglinide.
Substances that are inducers of CYP3A4, such as rifampicin, carbamazepine, barbiturates and St John's wort(Hypericum perforatum)are likely to decrease the plasma concentrations of darifenacin.
St John's wort is expected to decrease the plasma concentrations of darunavir or its pharmacoenhancers.
Elvitegravir is a modest inducer and may have the potential to induce CYP2C9 and/or inducible UGT enzymes;as such it may decrease the plasma concentration of substrates of these enzymes.
Letermovir may decrease the plasma concentrations of dabigatran and may decrease efficacy of dabigatran.
Substances that are inducers of CYP3A or P-gp decrease the plasma concentrations of mirabegron.
Carbamazepine has been shown to decrease the plasma concentrations of the active antipsychotic fraction of risperidone.
Enzyme inducers Substances that are inducers of CYP3A4, such as rifampicin, carbamazepine, barbiturates and St John's wort(Hypericum perforatum)are likely to decrease the plasma concentrations of darifenacin.
Strong or moderate inducers of CYP3A4 andP-gp may decrease the plasma levels and therapeutic effect of daclatasvir.
As such, elvitegravir may decrease the plasma concentration of substrates of CYP2C9(such as warfarin) or UGT(such as ethinyl estradiol).
Elvitegravir may have the potential to induce CYP2C9 and/or inducible uridine diphosphate glucuronosyltransferase(UGT) enzymes;as such it may decrease the plasma concentration of substrates of these enzymes.
With simultaneous use of colestyramine, colestipol andaluminum hydroxide, they decrease the plasma concentration of levothyroxine sodium due to inhibition of its absorption in the intestine.
Effects of vemurafenib on other medicinal products Vemurafenib may increase the plasma exposure of medicinal products predominantly metabolised by CYP1A2 and decrease the plasma exposure of medicines predominantly metabolised by CYP3A4.
Coadministration of haloperidol with potent enzyme inducers of CYP3A4 may gradually decrease the plasma concentrations of haloperidol to such an extent that efficacy may be reduced.
Inhibitors and inducers of CYP3A have the potential to respectively increase and decrease the plasma concentrations and, subsequently,the effects of midazolam requiring dose adjustments accordingly.
Strong inducers of CYP3A4, such as carbamazepine, enzalutamide, mitotane, St. John's wort, and/or strong inducers of CYP2C19, such as rifampin,administered concomitantly with cannabidiol may decrease the plasma concentrations of cannabidiol and decrease the effectiveness of cannabidiol.
Days of 600 mg once daily decreased the plasma concentrations of intravenous midazolam by about 60%.
In a clinical study, co-administration of a single dose 960 mg of vemurafenib with rifampicin,significantly decreased the plasma exposure of vemurafenib by approximately 40%.
Pre-treatment with rifampicin(600 mg once daily for 7 days),a potent inducer of P-gp, decreased the plasma exposure to afatinib by 34%(AUC0-∞) and 22%(Cmax) after administration of a single dose of 40 mg GIOTRIF.