Примери за използване на Dosing intervals на Английски и техните преводи на Български
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Dosing intervals should be modified according to clinical response and tolerability.
In certain cases, lower doses or longer dosing intervals may be required.
Use dosing intervals of 3- 4 hours(this corresponds to a maximum of 6 administrations per day).
Your doctor may cautiously shorten the dosing intervals depending on how you tolerate the treatment.
Dosing intervals and factor consumption remained similar in Study III compared to Study II.
IU/kg twice weekly is the proposed starting dose for prophylaxis in patients>12 years of age with dose levels and dosing intervals to be adjusted as clinically indicated.
The dose level and dosing intervals for surgery depend on the procedure and local practice.
Dosing intervals should be modified according to clinical response and tolerability(see sections 4.4 and 5.2).
If your doctor decides to further increase the dose up to 5 microgram, again dosing intervals of 3- 4 hours should be chosen initially and shortened depending on how you tolerate the treatment.
Dosing intervals and factor consumption remained similar in Study III(extension study) compared to Study I for both prophylactic regimens.
If a further increase in the dose up to 5.0 micrograms is indicated,again dosing intervals of at least 3 hours should be chosen initially and shortened according to individual tolerability.
Thereafter, dosing intervals may be shortened cautiously based on individual tolerability.
In 2 studies with extended interval dosing of epoetin alfa(3 times per week, once weekly, once every 2 weeks, and once every 4 weeks)some patients with longer dosing intervals did not maintain adequate haemoglobin levels and reached protocol-defined haemoglobin withdrawal criteria(0% in once weekly, 3.7% in once-every-2-weeks, and 3.3% in the once-every-4-weeks groups).
Some patients with more extended dosing intervals(greater than once weekly) of epoetin alfa may not maintain adequate haemoglobin levels(see section 5.1) and may require an increase in epoetin alfa dose. .
To reduce levodopa-related dopaminergic adverse reactions(e.g. dyskinesia, hallucinations, nausea, vomiting and orthostatic hypotension),it is often necessary to adjust the daily dose of levodopa by extending the dosing intervals and/or reducing the amount of levodopa per dose within the first days to first weeks after initiating treatment with Ongentys, according to the clinical condition of the patient(see section 4.2).
Some patients with more extended dosing intervals(greater than once weekly) of epoetin zeta may not maintain adequate haemoglobin levels(see section 5.1) and may require an increase in epoetin zeta dose. .
In 2 studies with extended interval dosing of EPREX(3 times per week, once weekly, once every 2 weeks, and once every 4 weeks)some patients with longer dosing intervals did not maintain adequate haemoglobin levels and reached protocol-defined haemoglobin withdrawal criteria(0% in once weekly, 3.7% in once-every-2-weeks, and 3.3% in the once-every-4-weeks groups).
Some patients with more extended dosing intervals(greater than once weekly) of epoetin alfa may not maintain adequate haemoglobin levels(see section 5.1) and may require an increase in epoetin alfa dose. .
In 2 studies with extended interval dosing of epoetin alfa(3 times per week, once weekly, once every 2 weeks, and once every 4 weeks)some patients with longer dosing intervals did not maintain adequate haemoglobin levels and reached protocol-defined haemoglobin withdrawal criteria(0% in once weekly, 3.7% in once-every-2-weeks, and 3.3% in the once-every-4-weeks groups).
Therefore, dose intervals of less than 4 weeks should be avoided.
Extending dose intervals may require an increase in dose. .
Extending dose intervals may require an increase in dose. .
Extending dose intervals may require an increase in dose. .
After steady state is reached,serum calcium concentrations remain constant over the dosing interval.
The effects were sustained over the 24 hour dosing interval.
In each trial, the effects were sustained over the 24 hour dosing interval.
The t1/2 decreases with decreasing concentrations within a dosing interval(see Table 16).
Injection technique and dosing interval.
In some cases shorter dose intervals or higher doses may be necessary.
Minimum 1 hour dosing interval.