Примери за използване на Hepatic metabolism на Английски и техните преводи на Български
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Pemetrexed undergoes limited hepatic metabolism.
Improves hepatic metabolism in people consuming alcohol;
Clearance is predominantly by hepatic metabolism.
Omeprazole suffers hepatic metabolism through the CYP 45o system.
Venlafaxine undergoes extensive hepatic metabolism.
Hepatic metabolism is the main route of clearance for abemaciclib.
Ropinirole is mainly eliminated by hepatic metabolism.
Biotransformation Hepatic metabolism of anidulafungin has not been observed.
Pemetrexed undergoes limited hepatic metabolism.
It undergoes extensive hepatic metabolism mainly by glucuronide conjugation.
Granisetron is cleared primarily by hepatic metabolism.
Hepatic metabolism contributes to a minor extent to the elimination of corifollitropin alfa.
Bictegravir is primarily eliminated by hepatic metabolism.
Valdecoxib is eliminated via hepatic metabolism with less than 5% unchanged valdecoxib recovered in the urine.
The presence of the acetate ester further protects it from hepatic metabolism.
Levetiracetam does not undergo hepatic metabolism to a major extent.
Elimination of cariprazine andits major active metabolites is mainly through hepatic metabolism.
Erlotinib is eliminated by hepatic metabolism and biliary excretion.
Pioglitazone undergoes extensive hepatic metabolism by hydroxylation of aliphatic methylene groups.
In vitro andin vivo studies indicate that palbociclib undergoes extensive hepatic metabolism in humans.
Thiotepa undergoes rapid and extensive hepatic metabolism and metabolites could be detected in urine within 1 hour after infusion.
The reason for this difference is unclear andpossibly related to an increased hepatic metabolism and excretion.
However, hepatic metabolism represents the major route of anagrelide clearance and liver function may therefore be expected to influence this process.
Talazoparib undergoes minimal hepatic metabolism in humans.
Studies in rats with a similar interferon alfa medicinal product(pegylated interferon alfa-2a)showed a primarily elimination via hepatic metabolism.
It is eliminated predominantly by hepatic metabolism(mainly CYP3A4).
Hepatic metabolism and biliary secretion are the primary routes of elimination of dabrafenib and its metabolites and patients with moderate to severe hepatic impairment may have increased exposure.
Phenytoin: Fluconazole inhibits the hepatic metabolism of phenytoin.
Based on minimal hepatic metabolism and the renal route of elimination for emtricitabine, it is unlikely that a dose adjustment would be required for Truvada in patients with hepatic impairment(see section 5.2).