Примери за използване на High tumour на Английски и техните преводи на Български
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Pre-phase treatment for patients with high tumour burden.
Patients with a high tumour burden should be considered to be at greater risk for TLS.
Patients with rapidly proliferating tumour and high tumour burden are at risk of TLS.
Low albumin and high tumour burden are generally indicative of disease severity.
The patients at risk of TLS andTFR are those with high tumour burden prior to treatment.
Patients with high tumour burden and rapidly proliferative tumour may be at increased risk of TLS.
Patients with rapidly proliferating tumour and high tumour burden are at risk of tumour lysis syndrome.
For patients with a high tumour burden, pre-medication to reduce uric acid levels and hydration is recommended prior to dosing(see section 4.4).
Pre-medication to reduce uric acid levels and hydration is recommended prior to dosing for patients with a high tumour burden(see section 4.2).
Patients with a history of renal insufficiency and high tumour burden may be at greater risk and should be treated with increased caution.
Factors associated with early deaths were ECOG performance status,fast progressive disease on prior platinum therapy and high tumour burden.
Risk factors for TLS include high tumour burden, pre-existing chronic renal insufficiency, oliguria, dehydration, hypotension, and acidic urine.
Patients with a high tumour burden and/or high circulating lymphocyte count in CLL[> 25 x 109/L] may be at increased risk of severe IRRs.
The improvement in OS was similar between nivolumab in combination with ipilimumab and nivolumab monotherapy in patients with high tumour PD-L1 expression(PD-L1≥ 1%).
To minimise risk of TLS,patients with elevated uric acid or high tumour burden should receive allopurinol, or an alternative prophylaxis, prior to Kymriah infusion.
The Committee for Medicinal products for Human Use(CHMP) decided that Fasturtec' s benefits are greater thanits risks for the treatment and prophylaxis of acute hyperuricaemia, in order to prevent acute renal failure, in patients with haematological malignancy with a high tumour burden and at risk of a rapid tumour lysis or shrinkage at initiation of chemotherapy.
To minimise risk of TLS,patients with elevated uric acid or high tumour burden should receive allopurinol, or an alternative prophylaxis, prior to YESCARTA infusion.
High tumour burden is defined as having at least one of the following: bulky tumour mass(> 7 cm), involvement of three or more nodal sites(each> 3 cm), systemic symptoms(weight loss> 10%, fever> 38°C for more than 8 days, or nocturnal sweats), splenomegaly beyond the umbilicus, major organ obstruction or compression syndrome, orbital or epidural involvement, serous effusion, or leukaemia.
Patients who are considered to be at risk of TLS(e.g. patients with a high tumour burden and/or a high circulating lymphocyte count[> 25 x 109/L] and/or renal impairment[CrCl< 70 mL/min]) should receive prophylaxis.
Treatment and prophylaxis of acute hyperuricaemia, in order to prevent acute renal failure, in adults, children and adolescents(aged 0 to 17 years)with haematological malignancy with a high tumour burden and at risk of a rapid tumour lysis or shrinkage at initiation of chemotherapy.
Patients with high tumour burden(e.g., any lymph node with a diameter≥5 cm or high absolute lymphocyte count[ALC≥25 x 109/l]) are at greater risk of TLS when initiating venetoclax.
Treatment and prophylaxis of acute hyperuricaemia, in order to prevent acute renal failure, in patients with haematological malignancy with a high tumour burden and at risk of a rapid tumour lysis or shrinkage at initiation of chemotherapy.
Patients with a high tumour burden and/or a high circulating lymphocyte count(> 25 x 109/L) and/or renal impairment(CrCl< 70 mL/min) are considered at risk of TLS and should receive prophylaxis.
In patients with a high tumour burden, prophylactic allopurinol therapy to control serum levels of uric acid, together with adequate or increased hydration, should be commenced 24 hours before the start of chemotherapy.
Patients with the highest tumour burden as measured by the percentage of bone marrow blast cells at baseline(≥ 90%) still had a clinically meaningful response with a CR/CRh* rate of 21.6%(CI 12.9- 32.7)(see figure 2).
The reason for the differential sensitivity of the tumour vasculature(high) versus normal vasculature(low) are currently unknown.
You have a high total amount of tumour throughout the body, including your bone marrow.
The most important advantage of the procedure for the patient is that it has little side effects while the effect of the drug on the tumour is high.
Your doctor may check if you have a high total amount of tumour throughout the body, including your bone marrow.