Примери за използване на Main circulating на Английски и техните преводи на Български
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Nilotinib is the main circulating component in the serum.
Following single andrepeated doses of trametinib, trametinib as parent is the main circulating component in plasma.
The main circulating compound in plasma is telithromycin.
Genotoxicity data on TCC and its main circulating metabolite SL18.0740(M1).
The main circulating compound in plasma is telithromycin.
Most nations were on a silver standard until the late 19th century with silver coin forming the main circulating currency.
Cabazitaxel is the main circulating compound in human plasma.
Until the late 19th century,most nations were on a silver standard with silver coins forming the main circulating currency.
The main circulating metabolite is formed by N-demethylation of sildenafil.
Even up until the late 19th century,most nations were on a silver standard as to their'money,' with silver coins making up the main circulating currency.
The main circulating metabolite is formed due to N-dimethylation of Sildenafil.
No effects of azithromycin(500 mg daily for 3 days) were observed on AUC, C max, T max, elimination rate constant,and further T½ sildenafil or its main circulating metabolite.
The main circulating active metabolite is formed as a result of N-demethylation of sildenafil.
New studies wereperformed in 2011 and 2012 regarding the genotoxicity of the parent compound(TCC), its main circulating metabolite SL18.0740 and the aglycone metabolite SL59.0955.
The elimination half life of the main circulating(inactive) metabolite was 8 hours after single and repeated administration.
In a relative bioavailability study in adults, the constituted solution of clopidogrel showed a similar extent andslightly higher rate of absorption of the main circulating(inactive) metabolite compared to the.
The elimination half-life of the main circulating metabolite was 8 hours after single and repeated administration.
The main circulating metabolite of sorafenib in plasma, the pyridine N-oxide, shows in vitro potency similar to that of sorafenib.
The elimination half-life of the main circulating(inactive) metabolite was 8 hours after single and repeated administration.
The main circulating metabolites of regorafenib in human plasma are M-2(N-oxide) and M-5(N-oxide and N-desmethyl), which are pharmacologically active and have similar concentrations as regorafenib at steady state.
The elimination halflife of the main circulating(inactive) metabolite was 8 hours after single and repeated administration.
Clopidogrel and the main circulating(inactive) metabolite bind reversibly in vitro to human plasma proteins(98% and 94% respectively).
The elimination half-life of the main circulating(inactive) metabolite was 8 hours after single and repeated administration.
Clopidogrel and the main circulating(inactive) metabolite bind reversibly in vitro to human plasma proteins(98% and 94% respectively).
The major metabolic pathway includes N-debutylation to form the main circulating active metabolite followed by oxidation, oxidative deamination to form the inactive propanoic acid metabolite, followed by oxidation, and direct oxidation.
The kinetics of the main circulating metabolite were linear(plasma concentrations increased in proportion to dose) in the dose range of 50 to 150 mg of clopidogrel.
Metabolism The main circulating metabolite in humans is the N-demethylated piperazine derivative, which shows similar in vitro potency to the parent.
Plasma levels of the main circulating metabolite together with the effect of clopidogrel on ADP-induced platelet aggregation and bleeding time were comparable between these groups.
After repeated doses of 75 mg clopidogrel per day, plasma levels of the main circulating metabolite were lower in subjects with severe renal disease(creatinine clearance from 5 to 15 ml/ min) compared to subjects with moderate renal disease(creatinine clearance from 30 to 60 ml/ min) and to levels observed in other studies with healthy subjects.
Estradiol: Estradiol is the main form of estrogen circulating in the body when a woman is premenopausal.