Примери за използване на Pregnant rats на Английски и техните преводи на Български
{-}
-
Medicine
-
Colloquial
-
Official
-
Ecclesiastic
-
Ecclesiastic
-
Computer
Yes. Pregnant rats.
Agomelatine passes into the placenta and foetuses of pregnant rats.
Studies in pregnant rats and rabbits showed that telbivudine crosses the placenta.
Crizotinib was not shown to be teratogenic in pregnant rats or rabbits.
In pregnant rats, no maternal or fetal toxicity was observed at doses up to 575 μg/kg/day.
Placental transfer of tezacaftor was observed in pregnant rats.
In pregnant rats, no maternal or foetal toxicity was observed at doses up to 575 µg/kg/day.
Alectinib caused embryo-foetal toxicity in pregnant rats and rabbits.
In pregnant rats, no maternal or fetal toxicity was observed at doses up to 575 µg/kg/day.
Trabectedin crossed the placenta when administered to pregnant rats.
Pregnant rats exposed to obesity hormone lose birth's protective effect on breast cancer.
Roflumilast has been demonstrated to cross the placenta in pregnant rats.
In pregnant rats, there were slight decreases in body weight and food consumption at the highest dose.
There was no evidence of transplacental transfer of oritavancin in pregnant rats.
Studies in pregnant rats and in guinea pigs with 3H-ketoconazole indicate that ketoconazole crosses the placenta.
However, daptomycin can cross the placenta in pregnant rats(see section 5.2).
In pregnant rats administered tasimelteon during the period of organogenesis, there were no effects on embryofoetal development.
Sunitinib(0.3, 1.0, 3.0 mg/kg/day) was evaluated in a pre-and postnatal development study in pregnant rats.
Radioactivity passed through the placenta in pregnant rats after administration of radioactively marked nicorandil.
In pregnant rats, simeprevir concentrations in placenta, fetal liver and foetus were lower compared to those observed in blood.
Testosterone has a masculinising effect on female rat foetuses when dosedsubcutaneously at 0.5 or 1 mg/ day(as the propionate ester) to pregnant rats during organogenesis.
A reproduction study in pregnant rats dosed from the time of uterine implantation through lactation showed reduced body weight gains in the offspring during the nursing period.
Larotrectinib was not teratogenic andembryotoxic when dosed daily during the period of organogenesis to pregnant rats and rabbits at maternotoxic doses, i.e. corresponding to 32-times(rats) and 16-times(rabbits) the human AUC at the recommended clinical dose.
When pregnant rats were exposed to buprenorphine through osmotic minipumps from gestation day 7 onwards, maternal food and water consumption was reduced on gestation days 7 to 20.
In an embryo-foetal development study in which pregnant rats were administered vismodegib daily during organogenesis, vismodegib crossed the placenta and was severely toxic to the conceptus.
Administration of cariprazine to pregnant rats during the period of organogenesis, throughout pregnancy and lactation at clinically relevant exposures decreased postnatal survival, birth weight, and post-weaning body weight of first generation pups.
Teratology studies have been performed by continuous intravenous infusion of eptifibatide in pregnant rats at total daily doses of up to 72 mg/ kg/ day(about 4 times the recommended maximum daily human dose on a body surface area basis) and in pregnant rabbits at total daily doses of up to 36 mg/ kg/ day(about 4 times the recommended maximum daily human dose on a body surface area basis).
In an embryo-foetal development study in which pregnant rats were administered daily doses of brigatinib during organogenesis; dose-related skeletal anomalies were observed at doses as low as approximately 0.7-times the human exposure by AUC at the 180 mg once daily dose.
In the pregnant rat, the transfer of 14C-riluzole across the placenta to the foetus has been detected.
In pregnant rat, systemic administration of travoprost at doses more than 200 times the clinical dose during the period of organogenesis resulted in an increased incidence of malformations.