Примери за използване на Strong inhibitors на Английски и техните преводи на Български
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Other strong inhibitors of.
Dose adjustment of Daklinza is recommended when coadministered with strong inhibitors of CYP3A4(see Table 4).
Strong inhibitors of CYP3A4 may increase the plasma levels of daclatasvir.
Co-administration with strong inhibitors of CYP3A4.
Strong inhibitors of CYP3A4 may lead to increased toxicity(see section 4.5).
Riociguat and its main metabolite are strong inhibitors of CYP1A1 in vitro.
The effect of strong inhibitors of these isozymes on axitinib pharmacokinetics has not been studied.
The dose of Daklinza should be reduced to 30 mg once daily when coadministered with strong inhibitors of CYP3A4.
Concomitant use of strong inhibitors of CYP2C8(e.g., gemfibrozil; see section 4.5).
Caution should be exercised when administering Parareg concomitantly with strong inhibitors or inducers of CYP3A4 and/or CYP1A2.
Co-administration of strong inhibitors of P-gp with Vemlidy is not recommended.
Concomitant medicinal products that are strong inducers or strong inhibitors of CYP3A should be avoided.
The use of strong inhibitors of OATP1B(e.g. ciclosporin) with Vosevi is not recommended(see section 4.4 and Table 2).
A potential pharmacokinetic interaction with strong inhibitors of UGT1A3 and UGT2B7 cannot be excluded.
Strong inhibitors(e.g. gemfibrozil) of CYP2C8 are to be avoided or used with caution during enzalutamide treatment.
These active substances are strong inhibitors of both CYP3A4 and P-gp(see section 4.4).
The dose of Daklinza should be reduced to 30 mg once daily when coadministered with atazanavir/ritonavir,atazanavir/cobicistat or other strong inhibitors of CYP3A4.
Co-administration of sirolimus with strong inhibitors of CYP3A4 or inducers of CYP3A4 is not recommended(see section 4.4).
Strong inhibitors of CYP3A and/or P-gp(e.g., voriconazole, itraconazole, posaconazole, clarithromycin, erythromycin, captopril, carvedilol, ritonavir, azithromycin) can increase gilteritinib plasma concentrations.
Concomitant administration of Uptravi with strong inhibitors of CYP2C8(e.g., gemfibrozil) is contraindicated(see section 4.3).
Other strong inhibitors of CYP3A4(e.g., itraconazole, clarithromycin, nefazodone, troleandomycin, ritonavir, nelfinavir) would be expected to behave similarly.
That Tasigna is metabolised by CYP3A4 and that strong inhibitors or inducers of this enzyme may significantly affect exposure to Tasigna.
If strong inhibitors of CYP1A2(e.g. ciprofloxacin, enoxacin and fluvoxamine) are co-administered with pomalidomide, reduce the dose of pomalidomide by 50%(see sections 4.5 and 5.2).
Caution is recommended in concomitant treatment with strong inhibitors of CYP2C9(e.g. fluconazole) and CYP3A4(e.g. itraconazole, ketoconazole, ritonavir, clarithromycin).
The effect of strong inhibitors of UGT1A3 and UGT2B7(valproic acid, probenecid, and fluconazole) on the exposure to selexipag and its active metabolite has not been studied.
Tamsulosin hydrochloride should not be given in combination with strong inhibitors of CYP3A4 in patients with poor metaboliser CYP2D6 phenotype.
Moderate or strong inhibitors of CYP3A4 significantly increase the plasma exposure of simeprevir, and moderate or strong inducers of CYP3A4 significantly reduce plasma exposure of simeprevir.
Co-administration of Viekirax with or without dasabuvir with strong inhibitors of CYP3A may increase paritaprevir concentrations(see section 4.3 and Table 2).
Co-administration of Tyverb with strong inhibitors of CYP3A4(e.g. ritonavir, saquinavir, telithromycin, ketoconazole, itraconazole, voriconazole, posaconazole, nefazodone) should be avoided.
Co-administration of EVOTAZ with medicinal products containing ritonavir or cobicistat,which are strong inhibitors of CYP3A, may result in additional boosting and increased plasma concentration of atazanavir.