Примери за използване на Potent inhibitors на Английски и техните преводи на Български
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P-gp potent inhibitors.
Hence, concomitant treatment of Votubia and potent inhibitors is not recommended.
Acetogenins are potent inhibitors of NADH oxidase of the plasma membranes of cancer cells.
Treated with drugs that are potent inhibitors of CYP3A4.
Potent inhibitors of transporter proteins are not expected to influence fingolimod disposition.
Other cytokines are potent inhibitors of IgE synthesis.
Potent inhibitors of P-gp, BCRP, OATP1B1 and/or OATP1B3 have the potential to increase the exposure to paritaprevir.
Patients on treatment with potent inhibitors of OATP1B1(e.g. cyclosporine).
Potent inhibitors of CYP3A4 activity decrease erlotinib metabolism and increase erlotinib plasma concentrations.
Concomitant treatment of Votubia and potent inhibitors is not recommended.
Inversely, potent inhibitors and inducers may substantially affect ivabradine plasma concentrations(see section 4.5).
Concomitant treatment of Afinitor and potent inhibitors is not recommended.
The concomitant use of potent inhibitors or potent inducers of CYP3A4 with vinflunine should be avoided(see section 4.5).
Hence, concomitant treatment of Afinitor and potent inhibitors is not recommended.
Other potent inhibitors of CYP2D6, such as fluoxetine and paroxetine, may be expected to have similar effects and similar dose reductions should therefore be applied.
Itraconazole and ketoconazole are potent inhibitors as well as substrates of CYP3A4.
Concomitant use of vardenafil with HIV protease inhibitors such as ritonavir and indinavir is contraindicated,as they are very potent inhibitors of CYP3A4(see section 4.5).
Co-administration of Yondelis with potent inhibitors of the enzyme CYP3A4 should be avoided(see section 4.5).
The polyglutamate forms are retained in cells andare even more potent inhibitors of TS and GARFT.
The possibility that more potent inhibitors of CYP3A4(i. e. ketoconazole, itraconazole, ritonavir) may increase the plasma concentration of amlodipine to a greater extent than diltiazem cannot be excluded.
The researchers present now macrocyclic peptides(MCIPs) as potent inhibitors of amyloid formation;
Other potent inhibitors of CYP3A4, such as itraconazole and HIV protease inhibitors, may be expected to have similar effects and similar dose reductions should therefore be applied.
Therefore, concomitant use of aliskiren and P-gp potent inhibitors is contraindicated(see section 4.3).
Potent inhibitors of cytochrome P450 3A4 increase the risk of myopathy and rhabdomyolysis by increasing the concentration of HMG-CoA reductase inhibitory activity in plasma during simvastatin therapy.
Therefore Cymbalta should not be administered in combination with potent inhibitors of CYP1A2 like fluvoxamine(see section 4.3).
Potent inhibitors of CYP3A4(e.g. ketoconazole, itraconazole, voriconazole, posaconazole, clarithromycin, telithromycin, nefazodone and HIV protease inhibitors) are likely to markedly increase plasma levels of budesonide and concomitant use should be avoided.
Therefore ARICLAIM should not be administered in combination with potent inhibitors of CYP1A2 like fluvoxamine(see section 4.3).
Potent inhibitors of CYP3A4(e.g. antivirals such as ritonavir, ritonavir-boosted darunavir and ritonavirboosted fosamprenavir) may increase the bioavailability of ketoconazole, these medicinal products should be used with caution when co-administered with ketoconazole and patients should be monitored closely for signs and symptoms of adrenal insuficiency.
Therefore Duloxetine Lilly should not be administered in combination with potent inhibitors of CYP1A2 like fluvoxamine see section.
There are no data on concomitant treatment with an inhibitor of CYP2D6 but potent inhibitors of this enzyme might cause increased plasma concentrations of gefitinib in CYP2D6 extensive metabolisers by about 2-fold(see section 5.2).