Примери за използване на Terminal phase на Английски и техните преводи на Български
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Lavern was diagnosed with cancer while in terminal phase.
The Ottoman Empire was now in terminal phase and at the mercy of the Europeans.
The terminal phase consists of a decline in plasma concentration with a half-life of approximately 2 hours.
It is therefore unknown how the terminal phase and the residual area were calculated.
The terminal phase has not been covered unambiguously due to lack of data beyond 24 hours in paediatric subjects< 6 years of age.
Moreover, in certain volunteers(based on the submitted data) the terminal phase was derived from Cmax.
Today, we are living in the terminal phase of the biggest debt bubble in the history of the planet.
These subjects had a Cmax concentration about 3-fold higher at approximately 7 hours with a terminal phase half-life of approximately 89 hours.
The mean apparent volume of distribution during the terminal phase(Vz/F) in healthy volunteers ranged from 968 to 2,140 L across dosing groups and studies.
Thereafter, plasma concentrations declined in a biphasic manner with a rapid distribution phase anda relatively slow terminal phase.
The apparent volume of distribution during the terminal phase(mean of 7.3 to 8.8 litres) was not dependent on the administered dose.
Thiamine is excreted in the urine through the alpha phase of 0.15 hours,the beta phase- after 1 hour in the terminal phase- for 2 days.
The apparent volume of distribution in the terminal phase following inhalation was almost 20-fold larger, which reflects the much slower elimination after inhalation.
Blood levels of fingolimod andfingolimod phosphate decline in parallel in the terminal phase, leading to similar half-lives for both.
Mean volume of distribution during the terminal phase(Vz) following a single intravenous administration to healthy subjects ranged from approximately 7 to 10 L across studies.
Following a single140 mg intravenous dose, the mean(SD) volume of distribution during the terminal phase(Vz) was estimated to be 3.86(0.77) l.
With lower terminal phase conductor using a jumper is moved to the upper part of the flue terminal machines or diluted through the distribution booths in the machines.
These subjects had a Cmax concentration about 3-fold higher at approximately 7 hours with a terminal phase half-life of approximately 89 hours.
Very soon there was inaugurated the terminal phase of nebular condensation, the period which always precedes the final segregation of these immense space aggregations of energy and matter.
Maximum desloratadine concentration was about 3-fold higher at approximately 7 hours with a terminal phase half-life of approximately 89 hours.
Autoinduction also results in a corresponding decrease in the terminal phase half-life of nevirapine in plasma from approximately 45 hours(single dose) to approximately 25-30 hours following multiple dosing with 200-400 mg/day.
After intravenous dosing, the steady-state volume of distribution of glycopyrronium was 83 litres andthe volume of distribution in the terminal phase was 376 litres.
The mean(% coefficient of variation) apparent volume of distribution during the terminal phase of lusutrombopag in healthy adult subjects(n= 16) was 39.5 L(23.5%).
With regards to the terminal phase being derived from Cmax in certain volunteers, this could be a matter of concern if the pharmacokinetic analysis applied had been compartmental, as it would suggest that a fast disposition phase did not exist in those cases compared with the remaining ones.
In contrast, intrathecal administration of 30 mg free cytarabine has shown a biphasic CSF concentration profile with a terminal phase half-life of about 3.4 hours.
The X-band upgrade was intended to improve the system's ability to collect intelligence data on the terminal phase of ballistic missile tests, since operation in X-band offers a better degree of resolution and target separation.
If the actual LOQ of the method is much lower than that assumed, this may result in a greater error factor,in particular for the determination of terminal phase of extrapolated line and residual area.
Following a single intravenous dose of 12.5 mgalogliptin to healthy subjects, the volume of distribution during the terminal phase was 417 L indicating that the drug is well distributed into tissues.
However, the CHMP noted that the Applicant did not properly determine the LOQ limits anddid not provide detailed information on the choice of points for the calculation of the terminal phase, nor on the points chosen for the individual profile and segments.
Benazeprilat concentrations decline biphasically:the initial fast phase represents elimination of free drug, while the terminal phase reflects the release of benazeprilat that was bound to ACE, mainly in the tissues.