Примери за използване на Tumour samples на Английски и техните преводи на Български
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Both ctDNA and tumour samples were evaluable for 652 patients out of 1060 screened.
Scientists at The Institute of Cancer Research, London, analysed tumour samples from 245 women with ER negative tumours. .
That means the old tumour samples couldn't be compared with normal DNA from the same patients.
The re-evaluation of treatment efficacy in RET-negative patients based on the re-analysis of archived tumour samples from the pivotal study D4200C00058.
Tumour samples from approximately 81% of patients were analysed retrospectively for KRAS expression.
Local or central testing of blood or tumour samples for BRCA1/2 mutations has been used in different studies.
Tumour samples from approximately 81% of patients were analysed retrospectively for KRAS expression, of which 55% were KRAS wild-type.
These reports are based on in vitro findings from human tumour samples, but are of uncertain significance in the clinical situation.
Fresh tumour samples for tumour genetic analysis from the most recent metastatic site in patients enrolled in the dose-comparison study should be collected.
In this study, the researchers looked at DNA andRNA sequencing data from 360 tumour samples from patients with metastatic castration-resistant prostate cancer.
The researchers analyzed tumour samples from more than 2,500 patients with estrogen receptor positive breast cancer, one of the most common forms of the disease.
Conflicting reports in the literature,based on in vitro findings from human tumour samples, suggest erythropoietins may play a role as tumour proliferators.
Prior to enrolment, breast tumour samples were required to be centrally confirmed for HER2-positive status defined as a score of 3+ by IHC or gene amplification by ISH.
Conflicting reports in the literature,based on in vitro findings from human tumour samples, suggest erythropoietins may play a role as tumour proliferators.
Tumour samples obtained from the primary resection of colorectal cancer were analysed for the presence of the seven most common activating mutations in the codon 12 and 13 of the KRAS gene.
However, in a follow-up study with fresh tumour samples, no relation between RB1 expression and tumour response was observed.
Tumour samples were evaluated for PD-L1 tumour cell expression, and for Merkel cell polyomavirus(MCV) using an investigational immunohistochemistry(IHC) assay.
In the study, published in the journal Cell, researchers looked at DNA andRNA sequencing data from 360 tumour samples from patients with metastatic castration-resistant prostate cancer.
Immunoscore® uses digital images of tumour samples and advanced software to measure the number of positive immune cells found at tumour sites.
For the assessment of the RAS status,mutations other than those on exon 2 of the KRAS gene were determined from all evaluable tumour samples within the KRAS exon 2 wild-type population(65%).
Tumour samples obtained from the primary resection of colorectal cancer were analysed for the presence of the seven most common activating mutations in the codon 12 and 13(Gly12Asp, Gly12Ala, Gly12Val, Gly12Ser, Gly12Arg, Gly12Cys, and Gly13Asp) of the KRAS gene by using an.
A predefined retrospective subset analysis of 143 patients of the 154 patients with wild-type KRAS(exon 2) mCRC was performed, where tumour samples from these patients were tested for additional RAS mutations.
Retrospective testing of patients with available tumour samples was performed using central testing and generated successful results in 341 patients, of which 95% had an eligible mutation(known[n=47] or likely pathogenic[n=277]) and 2 gBRCAwt patients were confirmed to have sBRCAm only.
A predefined retrospective subset analysis of 586 patients of the 597 patients with wild-type KRAS(exon 2) mCRC was performed, where tumour samples from these patients were tested for additional RAS and BRAF mutations as previously described.
Patients had a tumour sample with an EGFR mutation categorised as either exon 19 deletion(58%) or exon 21 L858R substitutions(42%).
In clinical trials,central testing for BRAF V600 mutation using a BRAF mutation assay was conducted on the most recent tumour sample available.
In the Phase II and III clinical trials,screening for eligibility required central testing for BRAF V600 mutation using a BRAF mutation assay conducted on the most recent tumour sample available.
There were 952 patients with HER2-negative tumours, and a total of 115 patients whose tumour HER2 status was unconfirmed(no tumour sample, no assay result, or other reason).
If a tumour sample is not evaluable, then circulating tumour DNA(ctDNA) obtained from a blood(plasma) sample may be used.
In one patient, multiple tissue samples from their brain tumour were compared to their CSF.