Примери коришћења Xenobiotic на Енглеском и њихови преводи на Српски
{-}
-
Colloquial
-
Ecclesiastic
-
Computer
-
Latin
-
Cyrillic
After phase II reactions, the xenobiotic conjugates may be further metabolised.
A xenobiotic is a chemical which is found in an organism but which is not normally produced or expected to be present in it.
Benefits may include antibiotic resistance, xenobiotic tolerance or the ability to use new metabolites.
A xenobiotic is a chemical substance found within an organism that is not naturally produced or expected to be present within the organism.
The benefits may be in the form of antibiotic resistance, xenobiotic tolerance or the ability to use new metabolites.
A xenobiotic is a foreign chemical substance found within an organism that is not normally naturally produced by or expected to be present within that organism.
Firstly, in contrast to the amazing substrate range of many of the enzymes involved in xenobiotic metabolism, it shows a narrow substrate specificity.
The enzymes of xenobiotic metabolism the glutathione S-transferases are important in agriculture, since they may produce resistance to pesticides and herbicides.
This system of enzymes acts in three stages to firstly oxidize the xenobiotic(phase I) and then conjugate water-soluble groups onto the molecule(phase II).
This modern biochemical research resulted in the identification of glutathione S-transferases in 1961, followed by the discovery of cytochrome P450s in 1962, andthe realization of their central role in xenobiotic metabolism in 1963.
The actions of some drugs as substrates orinhibitors of enzymes involved in xenobiotic metabolism are a common reason for hazardous drug interactions.
The modified water-soluble xenobiotic can then be pumped out of cells and in multicellular organisms may be further metabolized before being excreted(phase III).
The actions of some drugs as substrates orinhibitors of enzymes involved in xenobiotic metabolism are also responsible for a hazardous drug interactions.
The major challenge faced by xenobiotic detoxification systems is that they must be able to remove the almost-limitless number of xenobiotic compounds from the complex mixture of chemicals involved in normal metabolism.
These reactions often act to detoxify poisonous compounds(although in some cases the intermediates in xenobiotic metabolism can themselves cause toxic effects).
In subsequent phase II reactions,these activated xenobiotic metabolites are conjugated with charged species such as glutathione(GSH), sulfate, glycine, or glucuronic acid.
Factors that are thought to cause variation in the levels of GH and IGF-1 in the circulation include an individual's genetic make-up, the time of day, age, sex, exercise status, stress levels, nutrition level, body mass index(BMI), disease state, race,estrogen status, and xenobiotic intake.
Metabolic pathways are also important in environmental science, xenobiotic metabolism of microorganisms determines the pollutant will be broken down during bioremediation, or persist in the environment.
Xenobiotic metabolism(from the Greek xenos“stranger” and biotic“related to living beings”) is the set of metabolic pathways that modify the chemical structure of xenobiotics, which are compounds foreign to an organism's normal biochemistry, such as drugs and poisons.
These pathways are also important in environmental science, with the xenobiotic metabolism of microorganisms determining whether a pollutant will be broken down during bioremediation, or persist in the environment.
Esterases and amidase Epoxide hydrolase In subsequent phase II reactions,these activated xenobiotic metabolites are conjugated with charged species such as glutathione(GSH), sulfate, glycine, or glucuronic acid.
MTs have the capacity to bind both physiological(such as zinc, copper,selenium) and xenobiotic(such as cadmium, mercury, silver, arsenic) heavy metals through the thiol group of its cysteine residues, which represent nearly 30% of its constituent amino acid residues.