英語 での Heterozygous の使用例とその 日本語 への翻訳
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Heterozygous Familial Hypercholesterolemia.
So all the pea kids will be yellow heterozygous.
Two heterozygous parents together have a 25% risk for future offspring being affected.
Prev:Oncogenic bystander radiation effects in Patched heterozygous mouse cerebellum.
Heterozygous missense mutations in this gene cause Duane's retraction syndrome 2(DURS2).
Haldane's rule Hybrid sexes that are absent, rare, or sterile,are heterozygous.
PDE1B-/- and PDE1B+/-(heterozygous) mice also exhibited Morris maze spatial-learning deficits.
The authors note that validation studies of the tester involved patients who had been clinically diagnosed with sickle cell anaemia and control patients.Patients who are carriers of the sickle cell trait(heterozygous) were not included in these studies.
Adult mice heterozygous for mutations in either Notch1 or Cbf1 have deficits in spatial learning and memory.
The physical appearance and general behavior of PDE1B null and heterozygous mice was identical to that of the wild-type litter mates.
F1 heterozygous mice are crossed with CAG-Flp mice or CAG-Cre mice) to elminate drug resistant gene.
Even after 24 trials on day 6, null and heterozygous mice were not performing comparably to wild-type mice.
With heterozygous thalassemia, some of the clinical signs will not develop, due to partial inhibition(inhibition) of the manifestations of the"mutant" gene.
Exome sequencing has revealed that asubset of individuals can carry multiple heterozygous pathogenic variants in Fanconi anemia genes,[163] which may impact phenotypic presentation.
Conversely, heterozygous knockout plants and non-mutant plants did not reveal any resistance to these viruses.
RTS2 is caused by homozygous or compound heterozygous mutations in the RECQL4 helicase gene(8q24.3; detected in 60-65% of RTS patients).
Null and heterozygous mice, in contrast, showed less improvement each day than their wild-type controls, resulting in significant differences on test days 3 through 6.
More PDE1B null mice(6%) and heterozygous mice(6%) died within one week following birth compared to wild-type mice(2%).
If one of their heterozygous children marries a person also heterozygous for eye color, most of their children will have brown eyes but some will have blue eyes.
Compared with infected wild-type mice, heterozygous Eprs+/- mice infected with PR8 had decreased amounts of antiviral cytokines and increased amounts of virus.
Furthermore, Fut8 heterozygous mice are vulnerable to exposure to cigarette smoke(the highest risk factor for COPD) or experimental induction of emphysema by elastase. Whereas 6 months are required to experimentally induce emphysema by cigarette smoke in wild-type mice, only 3-month exposure causes similar lung pathology in Fut8-heterozygous mice 10.
In the second generation, where the two heterozygous kids marry, their babies could have any of the three possible genotypes, showing the two possible phenotypes in a three-to-one proportion.
They, who have only one copy(eg,from only one parent, heterozygous) have a normal life expectancy and intelligence, although the development of motor skills in children often takes longer and there is an increased risk of death during the first year of life due to problems with the respiratory system.