Ví dụ về việc sử dụng Capsid trong Tiếng anh và bản dịch của chúng sang Tiếng việt
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These vaccines use only the capsid proteins of the virus.
The capsid of pump(pump body and pump cover) constitutes the workshop of pump.
Most of the motor falls off after the packaging step is completed,allowing the tail to attach to the capsid.
The capsid and entire virus structure can be mechanically(physically) probed through atomic force microscopy.
A matrix composed of the viral protein p17 surrounds the capsid ensuring the integrity of the virion particle.[16].
For RNA viruses, each segment often codes for just a single protein andthey're usually found together in 1 capsid.
A matrix composed of anassociation of the viral protein p17 surrounds the capsid, ensuring the integrity of the virion particle.
Rotaviruses avoid this by not uncoating fully inside the cell andby releasing newly produced mRNA through pores in the particle's inner capsid.
Enfuvirtide binds to gp41 preventing the creation of an entry pore for the capsid of the virus, keeping it out of the cell.[2].
The Influenza B virus capsid is enveloped while its virion consists of an envelope, a matrix protein, a nucleoprotein complex, a nucleocapsid, and a polymerase complex.
In virtually all viruses,at least one of these proteins forms a shell(called a capsid) around the nucleic acid.
The image shows a cross section of the virus head, or capsid, and an artist's interpretation of the motor as it packages DNA into the virus.
The lower disc first attaches to the DNA and is then drawn upward by the upper disc,pushing the DNA into the virus's capsid in the process.
The motor is needed to insert DNA into the capsid of the T4 virus, which is called a bacteriophage because it infects bacteria.
In these people, the weakened virus can cause the original disease.[86] Biotechnology and genetic engineering techniques areused to produce"designer" vaccines that only have the capsid proteins of the virus.
In many viruses, but not all, the nucleic acid alone,stripped of its capsid, can infect(transfect) cells, although considerably less efficiently than can the intact virions.
For reasons unknown, Sputnik is unable to replicate and produce new virions in these bald viruses.[8] Virophage growth is deleterious to APMV and results in the production of abortive forms andabnormal capsid assembly of APMV.
At higher concentrations, ozone destroys the capsid, or exterior protein shell by oxidation so DNA(deoxyribonucleic acid), or RNA(ribonucleic acid) structures of the microorganism are affected.
Another unusual feature of Pandoraviruses is that theyhave no gene allowing them to build a protein like the capsid protein, which is the basic building block of traditional viruses.
To better understand the interplay between the capsid and the cell the virus enters, Juan Perilla, an assistant professor of chemistry and biochemistry at the University of Delaware, used two supercomputers to run a simulation.
Now, Dan Li of Ghent University, Ghent, Belgium and collaborators have shown that grapeseed extract does so by denaturing the capsid protein, which is the coat of the virus, thereby disabling the virus.
The common house mouse TNFα and human TNF are structurally different.[29] The 17-kilodalton(kDa) TNF protomers(185-amino acid-long) are composed of two antiparallel β-pleated sheets with antiparallel β-strands, forming a'jelly roll' β-structure, typical for the TNF family,but also found in viral capsid proteins.
The discovery, published in the journal Nature,was made by examining the atomic structure of the capsid and creating mutant HIV viruses, which allowed the team to see the behavior of the pores.
At the molecular level, viruses escape from herd immunity through antigenic drift, which is when mutations accumulate in the portion of the viral genome that encodes for the virus's surface antigen,typically a protein of the virus capsid, producing a change in the viral epitope.
They has found that a triplex fits between hexamers and pentamers at quasi-three-fold positions to cement the capsid together, and six copies of the small capsid protein VP26 form a ring on the top of the hexon to stabilize the capsid.
This alteration is mediated by the viral protease, which cleaves the Gag polyprotein precursor, allowing the freed parts to reassemble to form the core of the mature virus particle.[6]Bevirimat prevents this viral replication by specifically inhibiting cleavage of the capsid protein(CA) from the SP1 spacer protein.
TRIM5 present in the cytoplasm recognizes motifs within the capsid proteins and interferes with the uncoating process, therefore preventing successful reverse transcription and transport to the nucleus of the viral genome.[9][10] The exact mechanism of action has not been shown conclusively, but capsid protein from restricted viruses is removed by proteasome-dependent degradation.[11].
A virus particle, also called a virion, consists of genes made from DNA or RNA which are surrounded by a protective coat of protein called a capsid.[21] The capsid is made of many smaller, identical protein molecules called capsomers.
However, researchers at the Pasteur Institute in Paris isolated a previously unknown and genetically distinct retrovirus in patients with AIDS which was later named HIV."[3]Each virion comprises a viral envelope and associated matrix enclosing a capsid, which itself encloses two copies of the single-stranded RNA genome and several enzymes.
In one of the experiments done by inoculating Acanthamoeba polyphaga with water containing an original strain of APMV,it was discovered that several capsid layers accumulate asymmetrically on one side of the viral particle causing the virus to become ineffective.