Ví dụ về việc sử dụng Digoxin trong Tiếng anh và bản dịch của chúng sang Tiếng việt
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Digoxin in some cases.
If you are taking digoxin, talk with your doctor.
Digoxin for Treatment of heart failure in adults.
If you take celecoxib with digoxin, the levels of digoxin in your body may be increased.
Digoxin for Treatment of atrial fibrillation in adults.
Celecoxib is currently used for pain relief, while Digoxin is used to treat atrial fibrillation and heart failure.
Consequently, the digoxin may further deprive a body already depleted in potassium of this needed substance, or the potassium competition may cause digoxin to become toxic.
No pharmacokinetic interaction was observed between rivastigmine and digoxin, warfarin, diazepam, or fluoxetine in studies in healthy volunteers.
In these studies, the digoxin dose has been generally titrated according to the patient's age, lean body weight, and kidney function.
This is more likely to occur if you are taking this medicine for more than one year,or if you are taking this medicine together with digoxin(Lanoxin®) or certain diuretics or"water pills".
Tacrine had no major effect on digoxin or diazepam pharmacokinetics or the anticoagulant activity of warfarin.
When in the bloodstream, it is almost completely(99.9%) bound to plasma proteins,but apparently to different binding sites than warfarin, digoxin and other drugs with high plasma protein affinity.
Initial: 400 to 600 mcg of digoxin intravenously usually produces a detectable effect in 5 to 30 minutes with a maximal effect in 1 to 4 hours.
For example, in normal subjects, co-administration of rabeprazole 20 mg QD resulted in an approximately 30% decrease in the bioavailability of ketoconazole and increases in the AUC andCmax for digoxin of 19% and 29%, respectively.
When MICARDIS was co-administered with digoxin, median increases in digoxin peak plasma concentration(49%) and in trough concentration(20%) were observed.
Since flupirtin binds to proteins, one should take into account the possibility of its interaction with any other drugs taken simultaneously, especially with warfarin, diazepam,glibenclamide, digoxin, propranolol, benzylpenicillin and clonidine, because may increase their activity.
Digoxin is eliminated by Pgp; its AUC is increased by about 30% in combination with velpatasvir and sofosbuvir(although it is not clear which of the two is responsible for this effect).[1].
Unusually for a drug that has persisted from antiquity to the present day, digoxin is still extracted from foxgloves, as it's difficult for chemists to synthesise it in a cost-effective and efficient manner.
Digoxin: A single dose of eszopiclone 3 mg did not affect the pharmacokinetics of digoxin measured at steady state following dosing of 0.5 mg twice daily for one day and 0.25 mg daily for the next 6 days.
The potential for protein binding displacement of dexmedetomidine by fentanyl, ketorolac,theophylline, digoxin and lidocaine was explored in vitro, and negligible changes in the plasma protein binding of dexmedetomidine hydrochloride were observed.
I had digoxin originally, but I will go with furosemide[Lasix, Lo-Aqua], one of the first loop diuretics-- water pills-- which is still a very important drug for hypertension and heart failure," Benet says.
When using Nimulide externally, care must be taken when it is used together with methotrexate,phenytoin, digoxin, lithium preparations, cyclosporine, diuretics, hypoglycemic and antihypertensive drugs, and other nonsteroidal anti-inflammatory drugs.
Plasma digoxin levels of patients on concomitant therapy should be measured, and digoxin dosage should ordinarily be reduced when propafenone is started, especially if a relatively large digoxin dose is used or if plasma concentrations are relatively high.
No significant pharmacokinetic interactions were observed between levetiracetam or its major metabolite and concomitant medications.[28] The pharmacokinetic profile of levetiracetam is not influenced by phenytoin, phenobarbital, primidone, carbamazepine, valproic acid, lamotrigine,gabapentin, digoxin, ethinylestradiol, or warfarin.
While several controlled trials have shown digoxin to be effective in a proportion of patients treated for heart failure, the evidence base for digitoxin is not as strong, although it is presumed to be similarly effective.[1].
For those patients receiving cardiovasculardrug therapy including diuretics and/or digoxin and/or ACE inhibitors and/or angiotensin II antagonists, dosing of these drugs should be stabilised during the past two weeks prior to initiation of Nebivolol treatment.
Digoxin- Chemical Structure In detail, digoxin is a molecule of natural origin belonging to the class of digitalis glycosides, particular compounds so called because they are identified and isolated from plants belonging to the genus Digitalis( Digitalis lanata and Digitalis purpurea).
Drugs that may interact with clorazepate include, digoxin, disulfiram, fluoxetine, isoniazid, ketoconazole, levodopa, metoprolol, hormonal contraceptives, probenecid, propranolol, rifampin, theophylline, valproic acid.[3] Selective serotonin reuptake inhibitors, cimetidine, macrolide antibiotics and antimycotics inhibit the metabolism of benzodiazepines and may result in increased plasma levels with resultant enhancement of adverse effects.
Digoxin toxicity, also known as digoxin poisoning, is a type of poisoning that occurs in people who take too much of the medication digoxin or eat plants such as foxglove that contain a similar substance.[1][2] Symptoms are typically vague.[1] They may include vomiting, loss of appetite, confusion, blurred vision, changes in color perception, and decreased energy.[1] Potential complications include an irregular heartbeat, which can be either too fast or too slow.[1].
Antiarrhythmics, such as verapamil and digoxin Antiepileptics, such as phenobarbital or carbamazepine Antihistamines, such as doxylamine and clemastine Antihypertensives, such as atenolol and propranolol Ethanol Benzodiazepines, such as diazepam, clonazepam, nitrazepam, alprazolam, or lorazepam Chloramphenicol Chlorpromazine Cyclophosphamide Ciclosporin Digitoxin Doxorubicin Doxycycline Methoxyflurane Metronidazole Narcotic analgesics, such as morphine and oxycodone Quinine Steroids, such as prednisone and cortisone Theophylline Warfarin.