Ví dụ về việc sử dụng Have mutations trong Tiếng anh và bản dịch của chúng sang Tiếng việt
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Some patients' tumors have mutations that make them particularly sensitive to one drug or another.
In the United Sates,about 15% of patients with non-small cell lung cancer have mutations to the EGFR.
Cancer arises when cells have mutations in their DNA that allow them to start quickly proliferating.
All organisms regardless of their reproduction style can have mutations happen at any time.
Some silenced TEs are inactive because they have mutations that affect their ability to move from one chromosomal location to another;
This model is similar to what happens in humans-more than 90 percent of people with colorectal cancer also have mutations in the APC gene, the authors said.
These tumors also often have mutations in genes called TP53(a tumor suppressor gene) and ATRX(a DNA-protein complex remodeling gene).
About half of tumors in people who have never smoked have mutations that can be targeted by newer drugs.
If some of the cells have mutations that allow them to grow faster than others, a tumor may form during this process.
But people with fish odorsyndrome can't metabolize the smelly compound, because they have mutations in the gene that produces that enzyme.
People with type O blood have mutations in the ABO gene that prevent them from making the enzyme that would build either the A or B antigen.
Livingston at Dana-Farber, are finding that many of these non-BRCA families have mutations in genes that have a relationship with BRCA1.
Some non-small cell lung cancers have mutations in the genes NRTK-1 and NRTK-2 that can be treated with the targeted therapy larotrectinib(Vitrakvi).
In rare cases, Bethlem myopathy is inherited in an autosomal recessive pattern,which means both copies of the gene in each cell have mutations.
Almost all of the pancreatic cancers have mutations in KRAS, so that's an ideal situation from a screening point of view,” Dr. Vogelstein said.
The researchers also hope to learn more about the biology of the newly discovered dual-risk genetic variants by studying people who have mutations in those genes.
New research seems to show that dogs have mutations to equivalent genetic regions in humans where changes are known to trigger high sociability and somewhat reduced intelligence.
NeuroFix was later acquired by Aevi Genomic Medicine, which began clinical trials in 2016 in adolescents with ADHD, autism,or anxiety, who have mutations in the glutamate receptor gene.
However, these drugs don't help patients with cancers that have mutations in the KRAS gene, so doctors check the cancer cells for these mutations before they give either of these drugs.
The issue with genetic cancers is they have mutations in the genes, so these,‘police cells' go around trying to kill those abnormal cells, but it's not working, so those cancer cells grow without being told to die by these police cells.
ERBITUX is not approved totreat colorectal cancer in patients whose tumors have mutations in genes called RAS(often called"RAS mutant"), or in patients for whom the mutational status of the genes is not known.
The most dramaticresponses were seen in patients whose tumours had mutations in genes involved in repairing DNA.
Genotypic resistance: The genetic code of HIV has mutations that are linked to drug resistance.
By middle age, almost half of all cells had mutations in this gene.
Whether the cancer has mutations(changes) in certain genes, such as the epidermal growth factor receptor(EGFR) gene or the anaplastic lymphoma kinase(ALK) gene.
Looking at their genetic makeup, the investigators found that they all had mutations in the LSS gene, which normally encodes a specialized enzyme.
None of the participants had been treated for their cancer before they joined the trial, and none had mutations in their EGFR or ALK genes, and so could not qualify for targeted therapy.
And again, what she found was some of those individuals had mutations that were protective from birth that kept them, even though they had high lipid levels, and you can see this is an interesting way of thinking about how you could develop preventive therapies.
While the new variant has mutations to the spike glycoprotein, which is targeted by the three leading vaccines,[which?] the immune system produces antibodies to several regions of the protein in response to the vaccine, so it is thought to be unlikely that a single mutation would make the vaccines less effective.[1].