Eksempler på brug af NOAEL value på Engelsk og deres oversættelser til Dansk
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The study showed a NOAEL value of 0.0021 mg/kg/day.
The NOAEL value is found to 80 mg/kg body weight/day.
The study found,as described above, a NOAEL value of 5000 µg Ni/kg bw.
The NOAEL value for harmful effects is 240 mg/m³.
Based on these tests 400(286)mg/kg body weight/day can be regarded as NOAEL value.
The NOAEL value for harmful effects is 240 mg/mÂ3.
The critical impact of benzyl alcohol is thus lethargy NOAEL value 188 mg/kg body weight/day.
The NOAEL value for the dam was 1100 µg Ni/kg bw/day.
In the calculations the 420 mg/kg bw/day is applied knowing that no NOAEL value is specified.
A NOAEL value for these effects was not determined RAR2004.
A later study by American Biogenics Corp.(1988)likewise found a NOAEL value of 5000 µg/kg/day.
Using a NOAEL value of 462 mg/kg bw/day the margin of safety(MOS) is> 54000.
A two generation study with rats sets a NOAEL value of 8 mg/kg bw/day for testicular toxicity.
The NOAEL value for effects on kidneys, liver and blood at inhalation has been determined at 10 mg/m³ during animal trials.
The concentration is also far below the NOAEL value which is the lower effect limit for irritation.
Using the NOAEL value for contact with skin(based on test animals) the following dermal exposure of phenol in contact with skin is found.
In this scenario Margin of Safety is significantly below 100 based on NOAEL value for effects being toxic to reproduction.
Using the NOAEL value 7.6 mg/kg bw/day and the highest estimated uptake the margin of safety(MOS) is equal to or more than: 7.6/0.1 76.
An old study exists for rabbits of subcronic effects from dermal exposure butit was not possible to derive a NOAEL value ECB, 2004.
If it is not possible to define a NOAEL value in the tests, LOAEL is used in the assessment of the risk.
A NOAEL value of 0.315 mg Cu/kg/day was identified following a study regarding intake of copper sulphate from drinking water(during a period of 9 months) Olivares et al., 1998 in ATSDR, 2004.
Based on the above mentioned information a NOAEL value of 1100 µg/kg bw/day is assumed to be valid for use in this project.
During inhalation of hexane, irritation of the mucous membranes of the nose was observed in a test with repeated exposure and a NOAEL value of 1,762 mg/m³(IRIS 2004) was determined.
In this study a NOAEL value of 5000 Âμg/kg/day related to reduction in bodyweight in rats was reported the study was completed over a period of 2 years.
The risk assessment of nickel sulphate from 2005(Andersen et al., 2005b)gives a NOAEL value of 1100 µg/kg/day related to damaging effects on the foetus.
No exact NOAEL value for this impact is found but the NOAEL value is between 250 and 500 mg/kg body weight/day even if a single case of vomiting is seen here.
Both JECFA(2001) and the EU risk assessment report(ECB 2004)reach the same conclusion that the NOAEL value of 53 mg/kg bw/day is the preferred value for risk characterisation.
A NOAEL value of 500 mg/kg bw/day is found for p-xylenes for reproductive, neurological and other systemic effects in rats in a test of two-year' duration ATSDR, 2005; NTP, 1986b.
Regarding the offspring(dosed after the perinatal period), a NOAEL value of 2200 µg Ni/kg bw/day was identified(Larsen and Tyle, 2008- draft), since no effect was found in the offspring.
A NOAEL value of 1566 mg/kg bw/day is found based on a study of 90 days but at the same time indications of carcinogenic effect in male rats at 420 mg/kg bw are found in a two-years' study.