Eksempler på brug af Bone marrow depression på Engelsk og deres oversættelser til Dansk
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Bone marrow depression is the dose-limiting toxic effect of hydroxycarbamide.
In rare cases Remeron can cause disturbances in the production of blood cells bone marrow depression.
Bone marrow depression(granulocytopenia, agranulocytosis, aplastic anemia thrombocytopenia) Eosinophilia.
However, possible symptoms of overdose are expected to include nausea, vomiting,diarrhoea and severe bone marrow depression.
If you have bone marrow depression, blood vessel problems in the brain(including stroke), or severe immune system disease.
Suspension or modification of therapy should be considered when drug-induced bone marrow depression is detected see section 4.2.
Bone marrow depression Bone marrow depression, usually presenting as granulocytopenia or agranulocytosis, has been reported during treatment with Remeron.
There have been reports of aplastic anaemia and bone marrow depression in patients treated with CellCept, some of which have been fatal.
The manifestations of acute overdose include nausea, vomiting, diarrhoea, mucositis,gastrointestinal irritation and bleeding, and bone marrow depression.
Pancytopenia, Bone marrow depression, Anaphylactic shock, Psychotic reactions, Migraine, Olfactory nerve disorders, Hearing impaired, Vasculitis, Pancreatitis, Liver necrosis, Petechiae, Tendon rupture.
Patients receiving Myfenax should be instructed to report immediately any evidence of infection, unexpected bruising, bleeding orany other manifestation of bone marrow depression.
Delayed toxicity: Bone marrow depression; alopecia; hemorrhagic cystitis; sterility(may be temporary); pulmonary infiltrates and fibrosis; hyponatremia; leukemia; bladder cancer; inappropriate ADH secretion; cardiac toxicity; amenorrhea.
Concurrent use of hydroxycarbamide andother myelosuppressive medicinal products or radiation therapy may increase bone marrow depression, gastro-intestinal disturbances or mucositis.
Common symptoms of overdosage are nausea, vomiting, diarrhoea,severe bone marrow depression(including anaemia, thrombocytopenia, leukopenia, and agranulocytosis), acute renal insufficiency as well as irreversible neurologic toxicity(paraparesis/ quadriparesis), Guillan-Barré syndrome, and Brown-Séquard syndrome.
Laboratory follow-up including haematological surveillance and lipoproteins determination should also be performed in order to detect early manifestations of copper deficiency, such as anaemia and/ orleukopenia resulting from bone marrow depression, and decrease in HDL cholesterol and HDL/ total cholesterol ratio.
Neutropenia Caution should be exercised in patients with low leukocyte and/ or neutrophil counts for any reason, in patients receiving medicines known to cause neutropenia, in patients with a history of drug-induced bone marrow depression/ toxicity,in patients with bone marrow depression caused by concomitant illness, radiation therapy or chemotherapy and in patients with hypereosinophilic conditions or with myeloproliferative disease.
Cyklofosfamid(Cytoxan- Bristol-Myers Squibb Oncology; Neosar- Pharmacia)(p.396, Appendix 2; used in chemotherapy) Acute toxicity: Nausea and vomiting; Type 1(anaphylactoid) hypersensitivity; facial burning and metallic taste;visual blurring Delayed toxicity: Bone marrow depression; alopecia; hemorrhagic cystitis; sterility(may be temporary); pulmonary infiltrates and fibrosis; hyponatremia; leukemia; bladder cancer; inappropriate ADH secretion; cardiac toxicity; amenorrhea.
The side effects of cyclophosphamide are mainly depression of bone marrow and bladder problems.