Eksempler på brug af Rats and dogs på Engelsk og deres oversættelser til Dansk
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The liver was a target organ in rats and dogs.
In rats and dogs, Heinz bodies and/ or Howell-Jolly bodies were found.
Dose related toxicities on male reproductive organs were observed in mice, rats and dogs.
This keeps chicken predators such as the foxes, rats and dogs away so that they cannot be a threat to your chickens.
The effect of thalidomide on thyroid function was assessed in both rats and dogs.
In repeated-dose toxicology studies in mice, rats and dogs, there were only limited effects of treatment with darunavir.
Gastric mucosal injury(erosion, ulcers or inflammation)also was noted in rats and dogs.
In repe ated-dose toxicology studies in mice, rats and dogs, there were only limited effects of treatment with darunavir.
Bone toxicity was diagnosed as osteomalacia(monkeys) and reduced bone mineral density rats and dogs.
The radiolysis products of Sm-EDTMP showed a renal toxicity in rats and dogs with a no effect level of 2.5 mg/ kg.
Dietary studies with rats and dogs have shown that 2-hydroxyethyl acrylate has a low toxicity after repeated dosing via this route.
Single-cycle(5-day dosing, 23 days non-treatment), 3- and 6-cycle toxicity studies were conducted in rats and dogs.
Toxicology studies of clofarabine in mice, rats and dogs showed that rapidly proliferating tissues were the primary target organs of toxicity.
These effects were observed at exposures of 14 and 3 times the human daily dose based on the AUC in rats and dogs respectively.
In repeated dose toxicity studies in rats and dogs, the main undesirable effects of temoporfin were phototoxicityand adverse injection site reactions.
Single doses of 1500 mg/ kg(9000 mg/ m2) and 720 mg/ kg(14,400 mg/ m2)were tolerated without significant toxicity in rats and dogs, respectively.
Animal toxicology studies have been conducted with tipranavir alone, in mice, rats and dogs, and co- administered with ritonavir(3.75:1 w/ w ratio) in rats and dogs.
TMZ is more toxic to the rat and dog than to humans, and the clinical dose approximates the minimum lethal dose in rats and dogs. .
In preclinical studies in rats and dogs, Renagel at a dose of 10 times the maximum human doses reduced absorption of fat soluble vitamins D, E and K, and folic acid.
Degeneration was confined to mice exposed with at least twice the recommended human exposure;the kidney was unaffected in rats and dogs.
The Committee was informed of short term studies in rats and dogs and of long term studies in mice and rats with candelilla wax as a component of various chewing gum bases.
The biological efficacy of erythropoietin has been demonstrated after intravenous and subcutaneous administration in various animal models in vivo rats and dogs.
Systemic exposures of atazanavir in mice(males), rats, and dogs at doses associated with hepatic changes were at least equal to that observed in humans given 400 mg once daily.
Mild renal tubular degeneration was confined to mice exposed with at least twice the recommended human exposure;the kidney was unaffected in rats and dogs.
Zonisamide caused developmental abnormalities in mice, rats, and dogs, and was embryolethal in monkeys, when administered during the period of organogenesis at zonisamide dosage and maternal plasma levels similar to or lower than therapeutic levels in humans.
Animal toxicology studies have been conducted at exposures up to clinical exposure levels with darunavir alone, in mice, rats and dogs and in combination with ritonavir in rats and dogs.
In repeat-dose toxicity studies, conducted in mice, rats, and dogs, atazanavir-related findings were generally confined to the liverand included generally minimal to mild increases in serum bilirubin and liver enzymes, hepatocellular vacuolation and hypertrophy, and, in female mice only, hepatic single-cell necrosis.
In repeated-dose toxicity studies, dose-related liver changes(weight, centrilobular hypertrophy, occasionally necrosis), induction of hepatic drug metabolising enzymes and slightly decreased erythron parameters were seen in mice, rats and dogs.
The primary targets of toxicity included the bone marrow, lymphoreticular system, testes, the gastrointestinal tract and, at higher doses,which were lethal to 60% to 100% of rats and dogs tested, degeneration of the retina occurred.
Standard safety pharmacology experiments were performed under light protection in the mouse, rat and dog.