Exemplos de uso de Coagulation cascade em Inglês e suas traduções para o Português
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Coagulation cascade model based on cell surfaces.
The process mimics the last step of the coagulation cascade.
Factor XII is part of the coagulation cascade and activates factor XI and prekallikrein in vitro.
Calcium is also required at other points in the coagulation cascade.
These proteins are found in the coagulation cascade pathways and complement system.
There is a correlation between the complement system and the coagulation cascade.
Inhibition of factor Xa in the coagulation cascade reduces thrombin generation and thrombus formation.
Factor VII activation is present in the blood sample,triggering the coagulation cascade.
The activation of the coagulation cascade results in thrombin generation and subsequent fibrin formation.
It is important for stabilizing the formation of the fibrin polymer(clot)which culminates the coagulation cascade.
The platelet-rich plasma(prp)upon activation of the coagulation cascade has a three dimensional structure, the fibrin clot.
Factor X, also known by the eponym Stuart-Prower factor or as prothrombinase, thrombokinase or thromboplastin,is an enzyme() of the coagulation cascade.
This culminates in activation of thrombin and the coagulation cascade, which stimulates formation of thrombi and destruction of platelets.
The sulfated polysaccharides of algae have already been used in several applications, mainly by inhibiting the activity of certain enzymes,such as those related to the coagulation cascade.
Inhibition of factor Xa in the coagulation cascade reduces thrombin generation, prolongs clotting time and reduces the risk of thrombus formation.
All these alterations would generate a vascular thrombogenic setting,with the activation of coagulation cascade and vascular tonus modification.
Activation of the coagulation cascade has been associated with the development of multiple organ failure, with a poor prognosis in septic patients.
Markers of endothelial injury/dysfunction,platelet activation or activation of the coagulation cascade may be related to inflammatory activation.
It is important to note that the coagulation cascade model and common coagulation tests do not reflect the complexity of in vivo hemostasis.
Since thrombin(serine protease)enables the conversion of fibrinogen into fibrin during the coagulation cascade, its inhibition prevents the development of thrombus.
When a blood vessel is injured, the coagulation cascade takes place, and each clotting factor is activated on a specific order to form a blood clot.
The pathogenesis of this entity is still uncertain, and is related to previous surgery, trauma, paraneoplastic conditions,genetic mutations of the blood coagulation cascade, and excessive physical activity.
Heparin inhibits the Xa factor and thrombin,blocking the coagulation cascade at these levels with therapeutical purposes; hemorrhage is the main complication.
Considering that the coagulation cascade is activated during surgery(e.g. abdominoplasty), it would be interesting to start preoperative prophylaxis to prevent its activation.
Inhibition of Factor Xa interrupts the intrinsic and extrinsic pathway of the blood coagulation cascade, inhibiting both thrombin formation and development of thrombi.
In addition, changes in the coagulation cascade may occur, including increased thrombin activity, which also contributes to a hypercoagulable state.
In the immediate postoperative period,even with alterations in the coagulation cascade, the patient developed retained clot syndrome and needed exploratory thoracotomy.
The C protein pathway prevents exaggerated blood coagulation cascade activation, protecting against inadvertent clot formation by Va and VIIIa factors inactivation.
In kidneys, the induction of inflammatory processes andthe generation of ROS activate the coagulation cascade in the renal microvasculature, resulting in a state of hypoxia and hypotension.
While thrombosis by alteration of the coagulation cascade is predominant in the first, in the second, the starting point of thrombogenesis is the adhesion and aggregation of platelets.