Exemplos de uso de Complement activation em Inglês e suas traduções para o Português
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Complement activation might have a central pathogenetic role.
Attributed to the formation of IgG antibodies and/ or complement activation.
Complement activation initiated by the interaction of microbial ANTIGENS with COMPLEMENT C3B.
The activation of this receptor causes a pathogenic pathway with complement activation and cell damage.
Complement activation is considered to play a fundamental role in the initial phase of the inflammatory response in CABG-ECC.
The majority of these reactions can be attributed to the formation of IgG antibodies and/or complement activation.
Other studies have shown reduction in the complement activation to the use of another NO donor sodium nitroprusside 23.
Changes to its surface molecules may cause an immune response with antibody binding, complement activation and cell damage.
The potential for synthetic molecules to control complement activation is of interest to clinicians dealing with immune-mediated disorders.
Other complement activation pathways occur through proteases, such as plasmin, plasma calycrein, and elastase, which cleave and activate C3.
Chakraborti et al. have assessed the concept that the ischemia andreperfusion injuries play a fundamental role in mediating complement activation.
In RA, complement activation occurs initially through the classical pathway due to the presence of autoantibodies, IC, and apoptotic cells in the joint.
Although igg4 is a immunoglobulin subtype with low complement activation capacity, there is abundant evidence of this involvement in pmg.
Its pathogenesis is not yet fully elucidated andis currently considered as a result of immune complex deposition and complement activation.
Those proteins control the complement activation on cell surface and limit cell injury mediated by complement in the host tissue.
Some form of heart disease is found in 30% to 89% of patients with SLE,probably due to the deposition of immune complexes and complement activation.
The presence of immune complexes turns on complement activation that seems mandatory for the recruitment of effector T cells at the challenge site.
Lesion mechanism is probably multifactorial andit is believed that it is associated to the formation of immunocomplexes, complement activation and presence of cryoglobulines.
Endotoxin complement activation mainly through alternative and mannose-binding pathways leads to the accumulation of C3a and C5a, which induce endothelial damage.
The membrane attack complex MAC,which is formed at the end of the complement activation pathways, is more rapidly observed when reperfusion occurs.
Definition English: Complement activation initiated by the binding of COMPLEMENT C1 to ANTIGEN-ANTIBODY COMPLEXES at the COMPLEMENT C1Q subunit.
Verteporfin at more than 5 times the expected maximum plasma concentration in treated patients,caused a low level of complement activation in human blood in vitro.
The final two chapters describe molecules that control complement activation, for which analogues could potentially be designed and produced for therapeutic purposes.
In addition, it does not display any effect on other serine proteases,such as the digestive enzymes trypsin or chymotrypsin, or on complement activation by the classical or alternative pathways.
Among the various PRRs involved in opsonization, complement activation, and phagocytosis, the TLRs are distinguished by their central role in binding to pathogens and initiating the inflammatory response.
These observations suggested that MBL may have a direct toxic effect on the cells andthat the membrane complex attack resulting from complement activation may not be crucial to this effect.
Among the mechanisms mentioned are, complement activation, adhesion of plasma proteins and platelet destruction leading to thrombus formation and vascular injury and embolism from the formation of nitrogen bubbles in the blood.
The anti-inflammatory action results from deactivation of pro-inflammatory cytokines such as TNF-alpha,selectins secreted by leukocytes such as CD11b integrins such as ICAM-1 and attenuation of complement activation.
The pathogenesis of ln is a complex process that involves the deposition of autoantibodies in the glomeruli, complement activation, cell proliferation, production of proteins in the extracellular matrix and release of inflammatory cytokines.
Stimuli such as products of complement activation, basic substances, including some animals' poisons, certain neuropeptides, and several physical agents mechanical trauma, heat, and cold can activate mast cells independently of IgE binding.