Exemplos de uso de Thyroid follicular em Inglês e suas traduções para o Português
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Thyroid follicular cell adenomas were noted in male rats.
Inorganic iodine present in circulation enters the thyroid follicular cells, where it is organified.
Iodine excess blocks cell proliferation and inhibits hormone synthesis,while delays oncogenic effects of ret/ptc3 activation in thyroid follicular cells.
After a year on the use of the medication a thyroid follicular neoplasm and, subsequently, antinuclear antibodies emerged.
Administration of 300 mg/kg/day resulted in an increased incidence of thyroid follicular cell adenoma.
Hepatocellular and thyroid follicular cell adenomas observed in rats are considered to be a consequence of rat-specific mechanism related to hepatic CYP enzyme induction.
There were increased liver weights and dose-related thyroid follicular cell hypertrophy in rats.
Rats developed hepatocellular and thyroid follicular cell adenomas at> 2-times the daily human dose[90 mg] based on systemic exposure when dosed daily for approximately two years.
Braf induction induces high expression of mir-17-92 while high dose iodine blocks this effect in thyroid follicular cells.
In these murine models of ptc andlch, braf activacted is expressed in the thyroid follicular cells(tcb mouse), and in the myeloid cells cx3cr1+(frbraf mouse).
Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid.
It is believed that activated T lymphocytes directed against the thyroid follicular cells recognize and bind to similar antigens present in the orbital tissues.
In this study, we evaluated the influence of high dose iodine in mirnasunder braf oncogene activation, and its effects in thyroid follicular cell biology.
Erythrosine has been shown to cause an increase in the incidence of thyroid follicular adenomas in male rats when fed at high doses in a 2-generation long-term study.
There is the hypothesis that the iodine supplementation status in the population may be the determining factor of such a change in the prevalence of thyroid follicular carcinoma.
In rats administration of 1000 mg/kg/day resulted in increased incidences of thyroid follicular cell adenoma and carcinoma, relative to those for controls.
While there were no significant histopathological changes in the goats, in the cow vacuolation of Purkinje neurons of the cerebellum,pancreatic acinar cells, and thyroid follicular cells were observed.
Iodide uptake by thyroid follicular cells and cells of differentiated thyroid carcinoma is mediated by the sodium iodide symporter NIS, which is responsible for an active co-transport mechanism of the ion across the basolateral membrane.
Compared to untreated ovariectomized controls,estrogens and tamoxifen induced greater thyroid follicular cell height comparable to that observed in normal rats.
The mechanism of uptake of pertechnetate is the formation of the anion 99mTcO4,which is captured by the sodium-iodide symporter NIS- a transmembrane glycoprotein that actively transports anions to the interior of cells as in the thyroid follicular cells.
RET rearrangement in papillary thyroid cancer is an oncogene activation marker for thyroid follicular cells, particularly for PTC; however it presents low specificity as it has been found in other tumors and also in HT.
GD is the most common cause of thyrotoxicosis, and its pathogenesis includes formation of TRAbs,which bind to the TSH receptors at the thyroid follicular cell membrane, causing gland hyperfunction.
The incidence of the following tumours was also increased in female rats: thyroid follicular cell adenoma, carcinoma and combined adenoma or carcinoma, adrenal cortical combined adenoma or carcinoma, cervical schwannoma, uterine endometrial stromal polyp, and combined polyp or sarcoma.
According to the authors, that fact reinforces the accumulated damaging action on the DNA andleads to the assumption that aberrant genetic changes accumulate for a long time in the thyroid follicular epithelium, possibly as a precursor of PTC.
Regarding neoplasias, one man was diagnosed with femoral osteoid osteoma one year after the diagnosis of PM, andthree women were diagnosed with the following neoplasias: thyroid follicular carcinoma one year after PM; metastatic epidermoid carcinoma three years after PM; and renal neoplasia 15 years after PM.
Escape phenomenon" is believed to occur because of decreased inorganic iodine concentration inside the thyroid follicle below a critical threshold secondary todown-regulation of sodium-iodide symporter(NIS) on the basolateral membrane of the thyroid follicular cell.
Viral antigens were more frequently demonstrated in epidermal keratinocytes, epithelium of hair follicles and dendritic cells of the dermis of the ears and skin, histiocytes andlymphocytes in lymph nodes, thyroid follicular cells, in the cytoplasm of neurons and to a lesser extent, in glial cells in the cerebral cortex and hippocampus.
The histopathological lesions of thyroid and salivary glands evidence focal ordiffuse infiltration of T lymphocytes, suggesting the same autoimmune response directed to the thyroid follicular cells and the salivary gland epithelium, respectively.
The patients with extensive follicular thyroid carcinoma lesions or metastases may exhibit hyperthyroidism.
Papillary thyroid cancer and follicular thyroid cancer 13 November 2013.