Examples of using Light chains in English and their translations into Chinese
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The light chains remain intact and attached to the heavy chain. .
And the IgM isotype contains five heavy chains and five light chains.
Discuss which regions on the heavy and light chains come together to bind to specific isotopes.
The IgG molecule consists of two heavy chains and two or two light chains.
These identical immunoglobulins or light chains are also known as Monoclonal proteins or M proteins.
The IgG and IgE isotypes contain two heavy chains and two light chains;
These identical immunoglobulins or light chains are also known as Monoclonal proteins or M proteins.
Meanwhile, the antibody consists of two heavy chains and two kinds of light chains.
Kappa(K) and lambda(λ) light chains refer to the two major antibody light chain isotypes.
In humans,the IgA and IgD isotypes contain four heavy chains and four light chains;
Within a plasma cell, two light chains and two heavy chains combine to form an immunoglobulin.
All immunoglobulins are composed of four protein chains, two light chains and two heavy chains. .
Other types of light chains, such as the iota(ι) chain, are found in lower vertebrates like Chondrichthyes and Teleostei.
Usually, both a blood anda urine sample will be tested to detect free light chains and intact immunoglobulins.
Free light chains, Spielmann says, have half-lives of only two to six hours, so their presence is a marker of at-the-moment immune system activity.
Almost all patients(94%)had a reduction in M protein or free light chains, with 13 of 17 patients experiencing at least a 50% decrease.
It is a miniaturized version of human antibodies and consists of only two heavy chains, not two light chains and two heavy chains. .
Can serum free light chain testing be done at home or in my healthcare practitioner's office?
Comprising two heavy chain DVD polypeptides and two light chain DVD polypeptide DVD binding protein called DVD-Ig TM.
For their study,the researchers used the whole heavy chain and the C2 domain of the light chain.
Why would my healthcarepractitioner order a"baseline" serum free light chain test?
In a minority of cases,only one section of an immunoglobulin called a"free light chain" is produced in large amounts.
This may represent IgG or IgA, but the light chain type is almost always lambda.
The most important types are Gm(heavy chain) and km(light chain).
An abnormal ratio and increased levels of one serum free light chain are often associated with diseases.
This class I moleculeis a heterodimer consisting of a heavy chain and a light chain(beta-2 microglobulin).
For example, a chain with just one carbon atom in it(CH4)is the lightest chain, known as methane.
Nivolumab is a fully human monoclonal immunoglobulin G4 antibody to PD-1.[1] The gamma 1 heavy chain is91.8% unmodified human design while the kappa light chain is 98.9%.[2].
In certain embodiments, any one or more of the following residues may be substituted with cysteine:V205(Kabat numbering) of the light chain;