What is the translation of " ISOFORMS " in Danish?

• isoformer

Examples of using Isoforms in English and their translations into Danish

There are two isoforms of COX, COX-1, and COX-2.
Der findes to COX isoformer, COX- 1 og COX- 2.

It binds with high affinity to the VEGF-A isoforms e. g.
Det binder sig med høj affinitet til isoformer af VEGF- A f. eks.

In vitro results indicate that different CYP isoforms are able to catalyse the N-dealkylation of rotigotine.
In vitro- resultater viser, at forskellige CYP- isoformer er i stand til at katalysere rotigotins N- dealkylering.

Rivaroxaban neither inhibits nor induces any major CYP isoforms like CYP3A4.
Rivaroxaban hverken hæmmer eller inducerer væsentlige CYP- isoformer såsom CYP3A4.

In vitro, multiple cytochrome P-450 isoforms including CYP3A, CYP2C19/C9 and CYP2D6 are responsible for metabolism of nelfinavir.
In vitro er de forskellige isoformer af cytochrome P- 450, inklusive CYP3A, CYP2C19/ C9 og CYP2D6 ansvarlige for metaboliseringen af nelfinavir.

Production of the primary metabolite, ucb L057, is not supported by liver cytochrome P450 isoforms.
Dannelse af den primære metabolit, ucb L057 er ikke afhængig af lever cytochrom P450 isoformer.

This is predominantly via cytochrome P450 2C8 although other isoforms may be involved to a lesser degree.
Dette sker fortrinsvis via cytokrom P450 2C8, selvom andre isoformer kan være involveret i mindre grad.

In vitro, emtricitabine did not inhibit metabolism mediated by any of the following human CYP450 isoforms.
In vitro hæmmede emtricitabin ikke metabolisme medieret af en af de følgende humane CYP450- isoformer.

Sildenafil is a weak inhibitor of the cytochrome P450 isoforms 1A2, 2C9, 2C19, 2D6, 2E1 and 3A4 IC50> 150 μ M.
Sildenafil er en svag hæmmer af cytokrom P450- isoformer 1A2, 2C9, 2C19, 2D6, 2E1 og 3A4 IC50> 150 µM.

This reduces the possibility of detection by the urine test by lowering the percent of basic isoforms in the urine.
Dette reducerer muligheden for påvisning ved urintest ved at sænke procenten af basiske isoformer i urinen.

Ritonavir has a high affinity for several cytochrome P450(CYP) isoforms and may inhibit oxidation with the following ranked order.
Ritonavir har stor affinitet til flere cytokrom P450(CYP)- isoformer, angivet i aftagende rækkefølge, og kan hæmme oxidation.

In-vitro studies in human liver microsomes indicate that ertapenem does not inhibit metabolism mediated by any of the six major CYP isoforms.
In- vitro undersøgelser i humane levermikrosomer viser at ertapenem ikke hæmmer metabolismen medieret af de 6 primære CYP- isoformer.

Sildenafil metabolism is principally mediated by the cytochrome P450(CYP) isoforms 3A4(major route) and 2C9 minor route.
Sildenafils metabolisme finder overvejende sted via cytokrom P450(CYP) isoformer 3A4(primær vej) og 2C9 sekundær vej.

Vardenafil is metabolised predominantly by hepatic metabolism via cytochrome P450(CYP) isoform 3A4 with some contribution from CYP3A5 and CYP2C isoforms.
Vardenafil metaboliseres hovedsagelig i leveren via cytokrom P450(CYP)- isoformen 3A4 men også via CYP3A5- og CYP2C- isoformer.

It is unlikely that atosiban inhibits hepatic cytochrome P450 isoforms in humans see section 4.5.
Det er usandsynligt at atosiban hæmmer hepatisk cytochrom P450 isoformer i mennesker se afsnit 4. 5.

Vardenafil is metabolised predominantly by hepatic enzymes via cytochrome P450(CYP) isoform 3A4, with some contribution from CYP3A5 and CYP2C isoforms.
Vardenafil metaboliseres overvejende af leverenzymer via cytokrom P450(CYP)- isoformen 3A4 men også via CYP3A5- og CYP2C- isoformer.

Studies have confirmed that tadalafil does not inhibit or induce CYP450 isoforms, including CYP3A4, CYP1A2, CYP2D6, CYP2E1, CYP2C9 and CYP2C19.
Undersøgelser har bekræftet, at tadalafil ikke inhiberer eller inducerer CYP450- isoformerne CYP3A4, CYP1A2, CYP2D6, CYP2E1, CYP2C9 og CYP2C19.

Tadalafil is not expected to cause clinically significant inhibition or induction of the clearance of medicinal products metabolised by CYP450 isoforms.
Tadalafil forventes ikke at medføre en klinisk signifikant inhibition eller induktion af clearance for lægemidler, som metaboliseres via CYP450- isoformer.

Based on in vitro data, nelfinavir is unlikely to inhibit other cytochrome P450 isoforms at concentrations in the therapeutic range.
På baggrund af in vitro data er det usandsynligt, at nelfinavir hæmmer andre cytochrom P450 isoformer ved koncentrationer inden for det terapeutiske område.

In vitro studies in human liver microsomes indicate that tigecycline does not inhibit metabolism mediated by any of the following 6 cytochrome P450(CYP) isoforms.
In- vitro studier i humane levermikrosomer indikerer, at tigecyklin ikke hæmmer metaboliseringen medieret af nogle af følgende 6 cytokrom P450(CYP) isoformer.

Concurrent use of substances which are metabolised by CYP450 isoforms may result in higher or lower plasma levels of either masitinib or those substances.
Samtidig brug af stoffer, som metaboliseres ved CYP450- isoformer, kan give højere eller lavere plasmaniveauer af enten masitinib eller disse stoffer.

However, some of it acts in the stomach and also inhibiting cyclooxygenase-1 and its isoforms in the mucosa of the organ.
Men noget af det virker i maven, og også at inhibere cyclooxygenase-1 og dets isoformer i slimhinden af organet.

While apolipoproteins enhance the breakdown of beta amyloid, some isoforms are not very effective at this task(such as APOE4), leading to excess amyloid buildup in the brain.
Mens apolipoproteiner forbedrer nedbrydningen af betaamyloid, er nogle isoformer(såsom APOE4) ikke særligt effektive til dette, hvilket fører til ophobning af amyloid i hjernen.

In vitro studies have determined that doripenem does not inhibit or induce the activities of CYP isoforms 1A2, 2A6, 2C9, 2C19, 2D6, 2E1 or 3A4.
Det er i in vitro- forsøg påvist, at doripenem ikke inhiberer eller inducerer aktivitet i CYP- isoformerne 1A2, 2A6, 2C9, 2C19, 2D6, 2E1 eller 3A4.

Stavudine does not inhibit the major cytochrome P450 isoforms CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4; therefore, it is unlikely that clinically significant drug interactions will occur with drugs metabolised through these pathways.
Stavudin hæmmer ikke de fremherskende cytokrom P450 isoformer CYP1A2, CYP2C9, CYP2C19, CYP2D6 og CYP3A4; det er derfor usandsynligt, at klinisk signifikante lægemiddelinteraktioner vil optræde med stoffer, der metaboliseres via disse pathways.

The oxidative metabolism of laropiprant is catalysed primarily by CYP3A4, whereas several UGT isoforms(1A1, 1A3, 1A9 and 2B7) catalysed the acyl glucuronidation.
Laropiprants oxidative metabolisme katalyseres primært af CYP3A4, mens mange UGT- isoformer(1A1, 1A3, 1A9 og 2B7) katalyserede acylglucuronideringerne.

MISO(Mixture of Isoforms) is a probabilistic framework written in Python that quantitates the expression level of alternatively spliced genes from RNA-Seq data, and identifies differentially regulated isoforms or exons across samples. By modeling the….
MISO(Blanding af Isoformer) er en probabilistisk ramme skrevet i Python, der kvantificerer ekspressionsniveauet& nbsp; af alternativt splejsede gener fra RNA-Seq data, og identificerer differentielt regulerede isoformer eller exons tværs prà ̧ver. Ved at….

In vitro studies indicate that lumiracoxib is not a significant inhibitor of other cytochrome P450 isoforms, including CYP1A2, CYP2C8, CYP 2C19, CYP2D6, CYP2E1, and CYP3A4.
In vitro studier indicerer, at lumiracoxib ikke er en signifikant hæmmer af andre cytokrom P450- isoformer, inklusiv CYP1A2, CYP2C8, CYP2C19, CYP2D6, CYP2E1 og CYP3A4.

Metabolism The calculated in vitro Ki values for all CYP isoforms tested(CYP1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP2E1, CYP3A4/ 5 AND CYP4A9/ 11) indicated that sunitinib and its.
Metabolisme De kalkulerede in vitro Ki- værdier for alle undersøgte CYP- isoformer(CYP1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP2E1, CYP3A4/ 5 og CYP4A9/ 11) tyder på, at sunitinib og dets aktive hovedmetabolit i enhver klinisk relevant grad hæmmer metaboliseringen af lægemidler.

Therefore FABLYN is unlikely to alter the pharmacokinetics of medicinal products that are cleared by metabolism via these CYP isoforms, or are transported by MDR1 P-glycoprotein.
Det er derfor usandsynligt, at Fablyn ændrer farmakokinetikken af lægemidler, der metaboliseres via disse CYP- isoformer eller transporteres af MDR1 P- glycoprotein.

How to use "isoforms" in an English sentence

Ten different CARMEN isoforms have been identified.

Three isoforms of SOD have been found.

Phosphatidylinositol 3-kinase isoforms as novel drug targets.

These isoforms are produced by alternative splicing.

Two isoforms are produced by alternative splicing.

There are several isoforms of FGFR2 protein.

Three splice-variant isoforms have been identified. 1.

All isoforms interact with several 14-3-3 proteins.

Actin isoforms show >90% overall sequence homology.

Two alternatively-spliced isoforms have been described. 1.

How to use "isoformer" in a Danish sentence

Vi opnåede lignende resultater ved hjælp af YFP-mærkede versioner af de tre isoformer immunoprecipitated med GFP-Trap perler i tilstedeværelse af rekombinant cofilin og γ [32P] ATP (figur 4d).

For eksempel, er vist i figur 3B aktiveret fosforyleres (phospho) og total isoformer STAT3 og ERK1/2, som er centrale molekylære kendetegnende for musen ESC-lignende naive pluripotency.

Vi observerede en gruppe endogene LIMK2-1 i HEK-celler transficeret med HA-mærkede versioner af de LIMK2 isoformer (angivet med en pil i anti-PP1i blot; Figur 1b).

Figur 1: bevis for eksistensen af LIMK2-1-proteinet. (A) skematisk diagram over de tre isoformer af human LIMK2.

Figur 2: De tre isoformer af LIMK2 interagere med ROCK1.

Selv om LIMK2-1 viser kinaseaktivitet mod MBP, der kan sammenlignes med de to andre isoformer, er cofilin ikke et godt substrat for det.

Dette sker fortrinsvis via CYP2C8, selvom andre isoformer kan være involveret i mindre grad.

Tre isoformer af LIMK2 er produceret af alternative splejsning: LIMK2a, LIMK2b og LIMK2-1.

Anti-GFP immunoprecipiteret LIMK2 isoformer og cofilin eller MBP blev anvendt i kinaseanalysen.

De tre isoformer viste lignende transfektering effektivitet: 54% for LIMK2-49% for LIMK2b og 43% for LIMK2b.