Examples of using Based on in vitro in English and their translations into Dutch
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Based on in vitro studies, the degree of plasma protein binding has been reported to range from 88 to 98.
Artenimol and piperaquine were not genotoxic/clastogenic based on in vitro and in vivo testing.
Based on in vitro investigations florbetaben(18F)
Eltrombopag does not inhibit or induce CYP enzymes based on in vitro and in vivo data see section 4.5.
Based on in vitro data, sonidegib is not a substrate of P-gp,
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Based on in vitro data pasireotide appears to be a substrate of efflux transporter P-gp P-glycoprotein.
inducers of cytochrome P450 enzymes(CYPs) based on in vitro and in vivo studies.
Based on in vitro data, lesinurad may be a mild inducer of CYP2B6
Conflicting reports in the literature, based on in vitro findings from human tumour samples,
Based on in vitro studies, palonosetron does not inhibit
These reports are based on in vitro findings from human tumour samples,
Based on in vitro data, repaglinide appears to be a substrate for active hepatic uptake organic anion transporting protein OATP1B1.
These reports are based on in vitro findings from human tumour samples,
Based on in vitro data, betaine might interact with amino acids mixtures
Based on in vitro bazedoxifene plasma protein-binding characteristics,
Based on in vitro data, nelfinavir is unlikely to inhibit other cytochrome P450 isoforms at concentrations in the therapeutic range.
Based on in vitro bazedoxifene plasma protein binding characteristics,
Based on in vitro studies, nitisinone is not expected to inhibit CYP 1A2,
Based on in vitro and in vivo studies, raltegravir is eliminated mainly by metabolism via a UGT1A1-mediated glucuronidation pathway.
Based on in vitro studies, CYP3A4
Based on in vitro studies, interactions involving plasma protein binding are not expected to have any clinically relevant effects on lumiracoxib or co-administered drugs.
Based on in vitro IC50 and in vivo plasma Cmax values, pazopanib metabolites GSK1268992
Based on in vitro studies, the potential risk of inhibition by cabazitaxel at clinically relevant concentrations is possible towards medicinal products that are mainly substrate of CYP3A.
Based on in vitro and in vivo data, trametinib is unlikely to significantly affect the pharmacokinetics of other medicinal products via
Based on in vitro studies and pharmacokinetic data obtained in healthy volunteers the following table describes interference with laboratory tests that may be observed following a 5 g dose of hydroxocobalamin.
Based on in vitro data, cinacalcet is a strong inhibitor of CYP2D6,
Based on in vitro data pasireotide is not a substrate of the efflux transporter BCRP(breast cancer resistance protein)