Examples of using B-cell in English and their translations into German
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Can be of B-cell type(left)- or T-cell type right.
In adults, approximately 85% of NHL cases are of B-cell origin.
A B-cell binds an antigen-specific T-cell in order to present its antigen.
One type of whiteblood cell is called a B-lymphocyte, or B-cell.
The B-cell reaction is usually measured via specific antibody detection in patients' sera.
The safety databasecomprises data from patients with multiple myeloma or B-cell lymphocytic leukemia CLL.
The incidence of lymphoma(B-cell and T-cell) cases was higher in clinical trials than expected in the general population.
Pharmacology cross reference: An inhibitor of Bruton's tyrosine kinase, ibrutinib,is used to treat CLL and other B-cell non-Hodgkin lymphomas.
Lymphocytes repopulate over time with B-cell recovery usually completed within 6 months.
Each B-cell has up to 120,000 B-cell receptors on its surface. The activation of these receptors causes the cell to form antibodies.
Risk factors for the development of CNS relapses are T-ALL,mature B-cell ALL, and a high leukocyte count at the time of diagnosis.
ADCC steps First, the B-cell produces antibodies directed against specific antigens present on a pathogen or a foreign body.
The trial was conducted in 143 patients with relapsed or refractory low-grade or follicular non-Hodgkin's lymphoma(NHL),or transformed B-cell NHL.
Genes important for the initiation and maintenance of the B-cell identity and for plasmacellular differentiation are PAX5 and IRF4, respectively.
BCMA(B-cell maturation antigen) is a surface protein that is highly expressed in multiple myeloma cells and to which the selected antibodies specifically bind.
Preclinical studies haveshown that ibrutinib effectively inhibits malignant B-cell proliferation and survival in vivo as well as cell migration and substrate adhesion in vitro.
Stem cells(B-cell progenitors) in bone marrow lack the CD20 antigen, allowing healthy B-cells to regenerate after treatment and return to normal levels within several months.
Studies have demonstrated that, when antigen-expressing viral vectors are used,the elicited T- and B-cell responses are both wider and of a greater order of magnitude than after DNA immunization alone.
Stem cells(B-cell progenitors) in bone marrow lack the CD20 antigen, allowing healthy B-cells to regenerate after treatment and return to normal levels within several months.
During the continuous intravenous infusion over 4 weeks, the pharmacodynamic response was characterised by T-cell activation and initial redistribution,rapid peripheral B-cell depletion, and transient cytokine elevation.
While loss of Bob1 leads to impaired B-cell development and activation, over-expression of Bob1 could contribute to B-cell lymphomas.
A profound understanding of the B-cell receptor signal path may help us to design molecules that suppress interaction between receptors, enabling us to stop cancer-promoting signals," stated Jumaa, describing a possible clinical use of his research.
Another group of scientists headed by Dr. BenedettaAccordi from the University of Padua concentrated on children's B-cell ALL. In spite of the great strides forward in therapy in recent decades, about 30 percent of children suffering from this disease fail to respond to any conventional therapy.
Consequently, newborns should be monitored for B-cell depletion and vaccinations with live virus vaccines should be postponed until the infant's B-cell count has recovered see section 4.4.