Examples of using Fentanyl in English and their translations into German
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I found traces of fentanyl and heroin on the spoon.
Fentanyl plasma protein binding is estimated at approximately 60% in dogs.
All right, so you're saying our DOA... Fentanyl in her blood.
Fentanyl should be used with caution in patients with previous or pre-existing bradyarrythmias.
I'm thinking he switched the vial after she took the one he loaded with fentanyl.
People also translate
It's a combination of heroin and fentanyl, same proportions as found on the needle in his apartment.
Fentanyl pharmacokinetics appear to be similar with both single and multiple 24 hour applications.
Elderly patients Data from intravenous studies with fentanyl suggest that the elderly patients may have reduced clearance and a prolonged half-life.
Carcinogenicity studies(26-week dermal alternative bioassay in Tg. AC transgenic mice;two-year subcutaneous carcinogenicity study in rats) with fentanyl did not reveal any findings indicative of oncogenic potential.
Subsequently, fentanyl is redistributed between the deep tissue compartment(muscle and fat) and the plasma.
Patients were randomized to receive either remimazolam, midazolam,or placebo in addition to fentanyl, in order to achieve adequate sedation to start and perform the procedure.
Effentora like other fentanyl products can cause very severe breathing problems which can lead to death.
The Applicant provided data supporting the pharmacokinetic bridging strategy anddemonstrating that fentanyl delivery from Rapinyl provides effective pain relief in the target population.
Both the lowest effective fentanyl concentration and the concentration causing adverse reactions will increase with the development of increasing tolerance.
CYP3A4 substrates with a narrow therapeutic window(e.g. cyclosporine, pimozide, tacrolimus, sirolimus, ergotamine, diergotamine, fentanyl, alfentanil, terfenadine, bortezomib, docetaxel, quinidine) or warfarin and other coumarin derivatives see section 4.5.
Switching from other fentanyl containing products to Rapinyl must not occur at a 1:1 ratio because of different absorption profiles.
These may be concluded in the context of a potential patent dispute(as in today's Perindopril decision, see IP/14/799, and in the Lundbeck decision, see IP/13/563)or unrelated to any such dispute as in the Fentanyl decision.
Right now cryptocurrencies are used for buying fentanyl and other drugs so it is a rare technology that has caused deaths in a fairly direct way.
A marketing authorization application was submitted by the Applicant ProStrakan Ltd through the Decentralised Procedure for Rapinyl, a sublingual tablet containing 50, 100, 200, 300, 400,600 or 800 µg fentanyl, as citrate.
It is commonly agreed that Fentanyl is primarily responsible for the surge of deadly overdoses, as it is 10 to 50 times more potent than heroin[2] and it is undetectable to the bare eye.
The agreement therefore delayed the entry of a cheaper generic medicine for seventeen months andkept prices for fentanyl in the Netherlands artificially high- to the detriment of patients and taxpayers who finance the Dutch health system.
In a fertility and early embryonic development study in rats, a male-mediated effect was observed at high doses(300 mcg/kg/day, s.c.)and is consistent with the sedative effects of fentanyl in animal studies.
If patients with renal impairment receive transdermal fentanyl they should be observed carefully for signs of fentanyl toxicity and the dose reduced if necessary.
Opioids increase the tone and decrease the propulsive contractions of the smooth muscle of the gastrointestinal tract leading to a prolongation in gastrointestinal transit time,which may be responsible for the constipating effect of fentanyl.
Another published article of 52 elderly Japanese post-operative patients receiving continuous intravenous(IV) fentanyl infusion(0.5-1.5 µg/kg/h) showed increased fentanyl exposure in the CYP3A5*3 group(3*/3*) than in the 1* carrier group.
Each sublingual tablet contains 50 micrograms fentanyl(as citrate) 100 micrograms fentanyl(as citrate) 200 micrograms fentanyl(as citrate) 300 micrograms fentanyl(as citrate) 400 micrograms fentanyl(as citrate) 600 micrograms fentanyl(as citrate) 800 micrograms fentanyl as citrate.
Do not touch the sticky side of the system or the gels even after the you have stopped using the system and it has been removed,there is still enough fentanyl in the system to potentially cause life-threatening breathing difficulties or even death.
For example, in opioid-naïve volunteers morphine and fentanyl(pure agonists) produce dose-dependent depression of minute ventilation with apnea at high dose levels, but buprenorphine(partial agonist) causes dose-independent respiratory depression with a ceiling effect at higher doses.
The influence of hepatic and renal impairment on the pharmacokinetics of the medicinal product has not been evaluated; however,when administered intravenously the clearance of fentanyl has been shown to be altered in hepatic and renal impairment due to alterations in metabolic clearance and plasma proteins.
Regarding the co-administration with other opioids,it is acknowledged that the risk of combining fentanyl with a mixed agonist/ antagonist, like buprenorphine, nalbuphine and pentazocine, consists first in impaired analgesia, due to competitive antagonistic effects, and secondly in the onset of a withdrawal syndrome, which also represents a serious health concern.