Examples of using Inter-individual variability in English and their translations into Romanian
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Medicine
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Inter-individual variability in lomitapide AUC was approximately 50%.
The plasma concentration of duloxetine displays large inter-individual variability(see 5.2).
The inter-individual variability of voriconazole pharmacokinetics is high.
Excretion Systemic clearance ranged from 29.2 l/hr/m2 to 92.2 /hr/m2 depending on gender and age(inter-individual variability was 52.2%).
A high inter-individual variability of mRNA expression levels was observed(up to 600-fold).
Clinical experience suggests that the patient'sresponse to atypical and typical antipsychotic pharmacotherapy records an inter-individual variability.
There was a large inter-individual variability in AUC in subjects with renal impairment.
Distribution The volume of distribution of the central compartment was 12.4 l/m2 for women and17.5 l/m2 for men(inter-individual variability was 91.9%).
Inter-individual variability in peak and overall exposure is approximately 20-30%.
Population pharmacokinetic analysis revealed that BSA andgender were the most significant covariates to explain inter-individual variability in pharmacokinetic parameters.
Inter-individual variability(CV) of riociguat exposure(AUC) across all doses is approximately 60%.
No consistent gender effects on pharmacokinetics were observed in clinical studies with SANCUSO,with a large inter-individual variability reported in both sexes.
However, due to inter-individual variability, the effect may be clinically relevant in some individuals.
Following application of the patch on abdominal skin, maximum serum concentrations of testosterone are reached within 24-36 hours,with a wide inter-individual variability.
However, due to inter-individual variability in clearance, individualisation of dosage may be desirable.
The increase in steady state levels with the combined use of Diacomit, valproate, andclobazam is similar in adults and children, though inter-individual variability is marked.
Because of inter-individual variability in clearance in these patients, individualisation of dosage may be desirable.
However, a large component of inter-individual variability remained for CL2 after correction for CD19-positive cell counts and tumor lesion size.
However, due to inter-individual variability in the interaction, special attention on monitoring of INR should be performed the first weeks after initiation or ending concomitant treatment of warfarin and eslicarbazepine acetate.
