Examples of using Clarithromycin in English and their translations into Russian
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Clarithromycin As Inherent Component Of Anti-helicobacter Therapy.
Patients were assigned to receive clarithromycin at a dose of 500 mg twice a day for 10 days.
Cethromycin demonstrated more side effects,especially a distortion of the sense of taste, than clarithromycin;
If bismuth not available: concomitant therapy:PPI+ clarithromycin+ metronidazole+ amoxicillin for 14 days.
In blood serum of 22 patients with community-acquired pneumonia there has been determined the concentration of cefotaxime and clarithromycin.
This is due to the growing antibiotic resistance of HP, primarily- to clarithromycin, with possible regional features.
In this pilot study, clarithromycin improved subjective sleepiness in GABA-related hypersomnia.
The article is devoted to the review of current treatment regimens of Helicobacter pylori infection and place them clarithromycin.
The aim of the investigation is to study the pharmacokinetics of cefotaxime and clarithromycin in heavy smokers with community-acquired pneumonia.
Eradication rates have fallen to 70-85% over the last few years,in part due to increasing resistance to clarithromycin.
Reports from Asia suggest that 1 week of triple PPI therapy with clarithromycin and amoxicillin is still a useful form of treatment.
This scheme can be recommended as first-line therapy,especially in a population of individuals with high Helicobacter pylori resistance to clarithromycin.
In Brazil, patients with a history of allergy to penicillin receive PPI+ clarithromycin 500 mg and furazolidone 200 mg twice daily for 7 days.
Treatment of a Helicobacter pylori infection can be completed by taking a triple therapy combination of omeprazole,amoxicillin, and clarithromycin for 7-14 days.
Mutations which cause HP resistance to clarithromycin were identified in 39% of St. Petersburg residents, and only in 12.2% of residents of North Ossetia.
Among the analyzed isolates, 42.5% were resistant to metronidazole, 27.1%- to levofloxacin,25%- to clarithromycin, and 6.3%- to amoxicillin.
In 2013, a retrospective review evaluating longer-term clarithromycin use showed efficacy in a large percentage of patients with GABA-related hypersomnia.
There were some notable adverse events in seven studies:1 erythromycin demonstrated significant gastrointestinal side effects compared to clarithromycin in two studies;
In a test tube model, clarithromycin(an antibiotic approved by the FDA for the treatment of infections) was found to return the function of the GABA system to normal in patients with primary hypersomnias.
Sequential regimen: 10-day therapy with PPI+ amoxicillin for 5 days followed by PPI+ clarithromycin and a nitroimidazole(tinidazole) for 5 days.
Macrolide substances as azithromycin and clarithromycin are the most toxic compounds to algae as their half maximal concentration was lower than 1 mg/L.
Prescribers should be aware of drug resistance patterns in their own area(particularly with regard to clarithromycin) before deciding on a particular regimen.
PPI+ bismuth+ two antibiotics:amoxicillin+ clarithromycin, or metronidazole+ tetracycline.- May be cheaper than triple therapy.- More difficult to take than triple therapy.
Repaglinide is a major substrate of CYP3A4 and should not be administered concomitantly with gemfibrozil, clarithromycin or azole antifungals such as itraconazole or ketoconazole.
PPI+ two antibiotics:amoxicillin and clarithromycin, or metronidazole and clarithromycin.- Used and accepted worldwide.- Standard PPI-based therapy fails in up to 30% of patients.
Particular attention is paid to the prospects of new regimens,in particular the eradication treatment regimen with clarithromycin administration, and to the quality of antibacterial drugs.
In order to help further determine whether clarithromycin is truly beneficial for the treatment of narcolepsy and idiopathic hypersomnia, a small, double-blind, randomized, controlled clinical trial was completed in 2012.
Gastritis and diarrhoea were more common in the high-dose amoxicillin group(1 g three times a day)compared to the other three antibiotic groups(clarithromycin, azithromycin and levofloxacin).
The results showed significant differences in toxigenicity of HP strains and in their resistance to clarithromycin in different regions of Russia, which accounts for the differences in the effectiveness of standard therapy for HP infection.
The effectiveness of standard 1-line eradication schemes recommended by Russian and international consensuses for the treatment of Helicobacter pylori(HP) infection, including the proton pump inhibitor,amoxicillin and clarithromycin or metronidazole, has declined substantially over the last decade.